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首页> 外文期刊>The journal of sexual medicine >Sexual dysfunction and symptom impact in men with long-standing type 1 diabetes in the DCCT/EDIC cohort.
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Sexual dysfunction and symptom impact in men with long-standing type 1 diabetes in the DCCT/EDIC cohort.

机译：DCCT / EDIC队列中长期患有1型糖尿病的男性的性功能障碍和症状影响。

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INTRODUCTION: Male sexual dysfunction is a common complication of diabetes (DM), but the relative impact of erectile dysfunction (ED), orgasmic dysfunction (OD), and/or decreased libido (DL) on global sexual bother has not been assessed. AIM: To assess the relationship between ED, OD, and DL and overall sexual satisfaction in men with type 1 DM, and determine which form of dysfunction causes the most bother. METHODS: The study cohort consisted of 713 men with type 1 DM who completed the Diabetes Control and Complication Trial and then participated in the follow-up Epidemiology of Diabetes Interventions and Complications Study. In year 10 of EDIC, 583 (83%) completed a validated instrument assessing ED, OD, and DL and the bother these conditions cause. Statistical tests determined the concordance of function and bother in each domain, and the impact of each domain on overall sexual satisfaction. MAIN OUTCOME MEASURES: Patient-reported outcomes using responses to individual items of the International Index of Erectile Function (IIEF). RESULTS: ED was present in 34%, OD in 20%, and DL in 55%. When correlated with overall sexual satisfaction, ED had the highest weighted kappa (0.84, 95% confidence interval [CI] = 0.80-0.87), while OD (0.57, 95% CI = 0.51-0.63) and DL (0.55, 95%CI = 0.48-0.62) were considerably lower. Furthermore, the single item assessing confidence in getting and keeping an erection had the strongest correlation with overall sexual bother as well as specific erectile bother. CONCLUSIONS: ED, OD, and DL are highly prevalent in men with long-standing type I diabetes. All three sexual dysfunctions cause bother in men with DM, but ED causes more general sexual bother and likely has a greater overall impact on quality of life. Our data underscore the importance of asking men with DM about their sexual function and point to the need for further research to investigate disorders of orgasm and desire.
机译：简介：男性性功能障碍是糖尿病（DM）的常见并发症，但尚未评估勃起功能障碍（ED），性高潮功能障碍（OD）和/或性欲降低（DL）对总体性困扰的相对影响。目的：评估1型糖尿病男性的ED，OD和DL与总体性满意度之间的关系，并确定哪种形式的功能障碍引起最严重的困扰。方法：该研究队列由713名1型DM男性组成，他们完成了糖尿病控制和并发症试验，然后参加了糖尿病干预和并发症研究的后续流行病学研究。在EDIC的10年级中，有583名（83％）完成了一项评估ED，OD和DL的有效仪器，并困扰了这些情况。统计测试确定了每个领域的功能和烦恼的一致性，以及每个领域对总体性满意度的影响。主要观察指标：患者对国际勃起功能指数（IIEF）各个项目的反应报告的结果。结果：ED占34％，OD占20％，DL占55％。当与总体性满意度相关时，ED的加权卡帕值最高（0.84，95％的置信区间[CI] = 0.80-0.87），而OD（0.57，95％CI = 0.51-0.63）和DL（0.55，95％CI） = 0.48-0.62）则要低得多。此外，评估获得和保持勃起的信心的单个项目与总体性困扰以及特定的勃起困扰之间具有最强的相关性。结论：ED，OD和DL在长期存在I型糖尿病的男性中非常普遍。这三种性功能障碍都会引起DM男性的困扰，但是ED会引起更普遍的性困扰，并且可能对生活质量产生更大的总体影响。我们的数据强调了向患有DM的男性询问其性功能的重要性，并指出有必要进一步研究以调查性高潮和性欲障碍。

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