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Characteristics, behaviors, and attitudes of men bypassing the healthcare system when obtaining phosphodiesterase type 5 inhibitors.

机译:当获得5型磷酸二酯酶抑制剂时,男性的特征,行为和态度会绕过医疗保健系统。

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INTRODUCTION: Men may choose to bypass the healthcare system to obtain a phosphodiesterase type 5 inhibitor (PDE5i). AIM: Evaluate the characteristics and purchasing patterns of men obtaining a PDE5i without prior healthcare professional (HCP) interaction. MAIN OUTCOME MEASURES: Prior HCP interaction, defined as having a prescription for any PDE5i, having a PDE5i sample from a physician, or buying the PDE5i in a retail pharmacy; and erectile dysfunction (ED, the Massachusetts Male Aging Study single-item question) were assessed. A multivariate regression analysis determined predictive factors for PDE5i purchase without prior HCP interaction. Methods. A Web-based observational study was conducted in the United Kingdom, Germany, and Italy. RESULTS: Of the 11,899 participants, 1,252 (10.5% [95% CI, 10.0-11.1%]) reported PDE5i use in the last 6 months. PDE5is were obtained without prior HCP interaction by 403 users (32.3% [95% CI, 29.6-34.8%]); 65.5% of them had ED. Overall prevalence of men using PDE5is without HCP interaction was 3.0% (95% CI, 2.6-3.5%), 4.1% (95% CI, 3.5-4.6%), and 2.8% (95% CI, 2.1-3.5%) for men aged 18-34, 35-50, and >50 years, respectively (P = 0.0045). Predictive factors for obtaining a PDE5i without prior HCP interaction were embarrassment to speak to a physician (P = 0.0009) and the perception that this would be the cheapest way to get the medicine (P = 0.03). CONCLUSIONS: Based on these findings, it can be estimated that approximately 6 million men in Europe might currently bypass the healthcare system to obtain a PDE5i. In addition to the risks associated with use of PDE5is from uncontrolled sources, because most of these men have ED, they also miss the opportunity for important health information or medical follow-up. HCPs should actively address ED and offer treatment to discourage men from seeking uncontrolled sources of ED medicines.
机译:简介:男性可能选择绕过医疗保健系统,以获得5型磷酸二酯酶抑制剂(PDE5i)。目的:评估未经医疗专业人员(HCP)事先干预即可获得PDE5i的男性的特征和购买方式。主要观察指标:先前的HCP交互作用,定义为具有任何PDE5i的处方,从医师处获得PDE5i样品或在零售药房购买PDE5i。和勃起功能障碍(ED,马萨诸塞州男性衰老研究单项问题)进行了评估。多元回归分析确定了购买PDE5i的预测因素,而无需事先进行HCP交互。方法。在英国,德国和意大利进行了基于网络的观察性研究。结果:在11,899名参与者中,有1,252名(10.5%[95%CI,10.0-11.1%])报告了最近6个月内使用了PDE5i。 403位用户在没有事先进行HCP交互的情况下获得了PDE5(32.3%[95%CI,29.6-34.8%]);其中65.5%患有ED。在没有HCP相互作用的情况下,使用PDE5is的男性总体患病率为3.0%(95%CI,2.6-3.5%),4.1%(95%CI,3.5-4.6%)和2.8%(95%CI,2.1-3.5%)年龄分别为18-34岁,35-50岁和> 50岁的男性(P = 0.0045)。在没有事先进行HCP相互作用的情况下获得PDE5i的预测因素是与医生交谈时感到尴尬(P = 0.0009),以及人们认为这将是获得药物的最便宜方式(P = 0.03)。结论:基于这些发现,可以估计目前欧洲大约有600万男性可能绕过医疗保健系统而获得PDE5i。除了由于不受控制的来源而使用PDE5带来的风险外,由于这些男人中的大多数患有ED,他们还错过了获得重要健康信息或进行医学随访的机会。 HCP应积极应对ED,并提供治疗以阻止男性寻求不受控制的ED药物来源。

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