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首页> 外文期刊>The journal of sexual medicine >Tenderness as measured by pressure pain thresholds extends beyond the pelvis in chronic pelvic pain syndrome in men.
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Tenderness as measured by pressure pain thresholds extends beyond the pelvis in chronic pelvic pain syndrome in men.

机译：用压力疼痛阈值测量的柔韧性超出了男性慢性盆腔疼痛综合征的骨盆。

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INTRODUCTION: Urological Chronic Pelvic Pain Syndrome (UCPPS) in men is a common complaint, and causes significant impairment in quality of life. Until recently, the focus of research has primarily been on pain symptoms or underlying prostate pathology. However, new clinical phenotyping demonstrates pelvic tenderness to be an important component of UCPPS. Unfortunately, mechanisms underlying tenderness remain to be understood, and tenderness itself has not been well quantified. AIM: To validate the use of pressure pain thresholds as a method of measuring tenderness in UCPPS and to demonstrate that tenderness extends beyond the pelvis. METHODS: Fifty-five men diagnosed with UCPPS and 46 healthy controls were recruited through referrals and advertisements. Each participant filled out questionnaires and was assessed by a structured interview. In addition, all UCPPS men underwent urological assessment. MAIN OUTCOME MEASURES: Demographic information was collected as well as the National Institutes of Health-Chronic Prostatitis Symptom Index. Using a digital algometer, pressure pain thresholds on 10 genito-pelvic and one control site (deltoid) were measured. The four-glass test was used for all UCPPS men. RESULTS: UCPPS men had reliably lower pain thresholds compared to controls in all locations, including the deltoid. UCPPS men also demonstrated consistently lower overall pain thresholds regardless of location. Furthermore, pressure pain thresholds were able to correctly distinguish patients from controls 77% of the time. Prostate infection did not influence pain thresholds. CONCLUSIONS: Lower pelvic and nonpelvic thresholds suggest the involvement of a central mechanism in UCPPS. Overall, the data confirm the move away from a prostate-based view of UCPPS. This is supported by the failure to find threshold differences related to prostate infection. Pressure pain thresholds appear to be a promising method of assessing tenderness in UCPPS.
机译：简介：男性泌尿外科慢性盆腔痛综合征（UCPPS）是一种常见病，会严重影响生活质量。直到最近，研究的重点一直主要集中在疼痛症状或潜在的前列腺病理上。然而，新的临床表型表明骨盆压痛是UCPPS的重要组成部分。不幸的是，压痛的潜在机制仍有待了解，并且压痛本身尚未得到很好的量化。目的：验证使用压力痛阈值作为测量UCPPS压痛的方法，并证明压痛超出骨盆。方法：通过转诊和广告招募了55名被诊断为UCPPS的男性和46名健康对照。每个参与者填写问卷并通过结构化访谈进行评估。此外，所有UCPPS男性均接受了泌尿科评估。主要观察指标：收集人口统计学信息以及美国国立卫生研究院-慢性前列腺炎症状指数。使用数字血压计，测量10个生殖器骨盆和一个对照部位（三角肌）的压力疼痛阈值。所有UCPPS男性均使用四杯测试。结果：与包括三角肌在内的所有位置的对照组相比，UCPPS男性的疼痛阈值确实较低。无论身在何处，UCPPS男性都表现出持续降低的总体疼痛阈值。此外，压力疼痛阈值能够在77％的时间内正确区分患者与对照组。前列腺感染不影响疼痛阈值。结论：较低的骨盆和非骨盆阈值提示UCPPS中涉及一种中心机制。总体而言，数据证实已脱离基于前列腺的UCPPS。未能找到与前列腺感染相关的阈值差异支持了这一点。压力疼痛阈值似乎是评估UCPPS压痛的有前途的方法。

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