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首页> 外文期刊>The journal of sexual medicine >Stronger evidence for small fiber sensory neuropathy in restless genital syndrome: two case reports in males.
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Stronger evidence for small fiber sensory neuropathy in restless genital syndrome: two case reports in males.

机译：躁动性生殖器综合征中的小纤维感觉神经病的更有力证据：男性两例。

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INTRODUCTION: Restless genital syndrome (ReGS) is characterized by unwanted, unpleasant genital sensations, restless legs, and/or overactive bladder, as well as neuropathy of the dorsal nerve of the clitoris. So far, ReGS has only been reported in females. AIM: To report the occurrence of ReGS in two males. METHODS: Two males with unwanted genital sensations presented in our clinic. In-depth interview, routine and hormonal investigations, electro-encephalography, magnetic resonance imaging of brain and pelvis, manual examination of the pubic bone, and sensory testing of genital dermatomes were performed. In both males, conventional transcutaneous electrical nerve stimulation was applied bilaterally at the pudendal dermatome. MAIN OUTCOME MEASURES: Oral report, questionnaire on frequency and intensity of restless genital feelings, restless legs, overactive bladder, and satisfaction with the transcutaneous electrical nerve stimulation (TENS) treatment. RESULTS: ReGS in a 74-year-old male manifested as unpleasant genital sensations of being on the edge of an orgasm with overactive bladder, in the absence of erection and ejaculation. Genital sensory testing elicited bilateral points of static mechanical hyperesthesia in the pudendal dermatome. Manual examination of the dorsal nerve of the penis (DNP) elicited the genital sensations. TENS application resulted in a 90% reduction of genital sensations and complaints of overactive bladder syndrome (OAB). ReGS in a 38-year-old male manifested as unwanted and unpleasant spontaneous ejaculations and complaints of OAB. Genital sensory testing elicited bilateral points of static mechanical hyperesthesia in the pudendal dermatome. Manual examination of the DNP elicited the genital sensations. TENS application had no effect on genital complaints and complaints of OAB. CONCLUSIONS: ReGS is not a typical female disorder as it also affects males. This notion and the finding of typical sensory abnormalities of the genital end branches of the pudendal nerve in males and females--as previously reported--provides strong evidence for Small Fiber Sensory Neuropathy as a common cause of ReGS.
机译：简介：不安生殖器综合症（ReGS）的特征是不想要的，不愉快的生殖器感觉，腿不安和/或膀胱过度活动，以及阴蒂背神经的神经病变。到目前为止，ReGS仅在女性中报道。目的：报道两名男性中ReGS的发生。方法：我们诊所介绍了两名男性，他们有不想要的生殖器感觉。进行了深入的访谈，常规和激素检查，脑电图检查，大脑和骨盆的磁共振成像，耻骨的手动检查以及生殖器皮肤切开术的感觉测试。在两名男性中，常规的经皮电神经刺激在阴部皮刀两侧进行。主要观察指标：口头报告，关于不安的生殖器感觉，不安的双腿，膀胱过度活动的频率和强度的问卷，以及对经皮神经电刺激治疗的满意度。结果：一名74岁男性的ReGS表现为在没有勃起和射精的情况下，在膀胱过度活跃的性高潮边缘出现了令人不快的生殖器感觉。生殖器感觉测试在阴部皮肤刀中引起静态机械性感觉异常的双侧点。手动检查阴茎背神经（DNP）会引起生殖器感觉。 TENS的应用可将生殖器感觉和膀胱过度活动症候群（OAB）的症状减少90％。一名38岁男性中的ReGS表现为不希望和不愉快的自发射精和OAB的主诉。生殖器感官测试在阴部皮刀中引起静态机械感觉异常的双侧点。手动检查DNP会引起生殖器感觉。 TENS的申请对生殖器疾病和OAB症状没有影响。结论：ReGS不是典型的女性疾病，因为它也影响男性。正如先前报道的那样，这一观点以及对男性和女性阴部神经生殖器末端分支典型感觉异常的发现，为小纤维感觉神经病是ReGS的常见原因提供了有力证据。

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