• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>The journal of sexual medicine >Ultrastructural and quantitative study of clitoral cavernous tissue from living subjects.
【24h】

Ultrastructural and quantitative study of clitoral cavernous tissue from living subjects.

机译：活体对象阴蒂海绵体组织的超微结构和定量研究。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

INTRODUCTION: There has never been an investigation about the in vivo clitoral structure. AIM: To study the "in vivo" age-related structural changes of the clitoris in healthy women and in those affected by metabolic disorders. METHODS: Forty-three women subgrouping in (i) five teenagers, aged 14-18; (ii) eight young premenopausal women, aged 23-32; (iii) 10 premenopausal women, aged 38-47; (iv) nine diabetic premenopausal women, aged 27-43; and (v) 11 naturally postmenopausal women aged 51-55. Each woman underwent microbiopsy of the clitoral body by means of an 18G needle, length 100 mm, using a semiautomatic gun during total anesthesia for a benign gynecological pathology. The tissue removed was processed for electron microscopy. A morphometric procedure was used on electron micrographs. MAIN OUTCOME MEASURE: Micro ultrastructure observation of clitoral tissue. RESULTS: The cavernous tissue from the teenagers and young women showed large amounts of smooth muscle cells (SMCs). The intercellular connective tissue showed scanty, small isometric collagen fibers and amorphous extracellular matrix. In the premenopausal diabetic women, ultrastructural abnormalities of SMCs were observed, consisting of increase of glycogen deposits, infolding cell borders, and cytoplasmic vacuoles. Moreover, the intercellular connective tissue was increased by densely packed collagen fibers. Finally, in the healthy, natural postmenopausal women, the SMCs were moderately reduced in number. We observed age-related structural changes of the vascular spaces and of the vascular lacunae. The SMC mean thickness was reduced with age; vascular abnormalities appeared to be correlated with the presence of metabolic diseases, such as diabetes. CONCLUSION: Our "in vivo" study could help to understand some aspects of the physiology of the clitoris and its role in sexual response. Apart from data obtained by studying healthy women and women affected by diabetes, other investigations are needed to study subgroups of otherwise healthy sexually dysfunctional women.
机译：引言：从未有关于体内阴蒂结构的研究。目的：研究健康女性和代谢异常患者中阴蒂的“体内”与年龄相关的结构变化。方法：（i）五名年龄在14-18岁的青少年中的43名妇女分组; （ii）八名年轻的绝经前妇女，年龄在23-32岁之间; （iii）10名绝经前妇女，年龄在38-47岁之间; （iv）9名糖尿病绝经前妇女，年龄在27-43岁之间; （v）11名自然界绝经后女性，年龄在51-55岁之间。每个妇女在全麻期间使用半自动枪用一根长100 mm的18G针对阴蒂进行活检，以进行良性妇科病理学检查。将取出的组织进行电子显微镜检查。在电子显微照片上使用形态计量学程序。主要观察指标：阴蒂组织的超微结构观察。结果：青少年和年轻妇女的海绵状组织显示出大量的平滑肌细胞（SMC）。细胞间的结缔组织显示出稀疏，小的等距胶原纤维和无定形的细胞外基质。在绝经前的糖尿病妇女中，观察到SMC的超微结构异常，包括糖原沉积增加，细胞边界折叠和细胞质液泡。此外，紧密堆积的胶原纤维增加了细胞间的结缔组织。最后，在健康，自然的绝经后妇女中，SMC的数量有所减少。我们观察到了与年龄相关的血管间隙和血管腔的结构变化。 SMC的平均厚度随着年龄的增长而降低;血管异常似乎与代谢性疾病（例如糖尿病）的存在相关。结论：我们的“体内”研究可以帮助理解阴蒂生理学的某些方面及其在性反应中的作用。除了通过研究健康妇女和患有糖尿病的妇女获得的数据之外，还需要其他研究来研究其他健康的性功能障碍妇女的亚组。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号