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What is the impact on sexual function of laparoscopic treatment and subsequent combined oral contraceptive therapy in women with deep infiltrating endometriosis?

机译:腹腔镜治疗及随后的联合口服避孕药治疗对深层浸润性子宫内膜异位症患者的性功能有何影响?

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Introduction. Deep infiltrating endometriosis (DIE) is a form of endometriosis in which the lesion penetrates for more than 5mm under the peritoneal surface. It is a chronic disease which can impair women's sexual function. There is a growing body of evidence supporting combined surgical/medical treatment in the management of DIE. Aims. The aims of this article are to evaluate the impact of the laparoscopic full excision of endometriosis and postoperative combined oral contraceptives (COC) administration on sexual function in patients with DIE and to compare sexual function outcomes of women submitted to intestinal resection and nodule excision. Methods. It is a prospective cohort study in a tertiary care university hospital on 106 sexually active women, with histologically confirmed DIE, managed by laparoscopy and subsequent COC therapy for 6 months. Patients filled preoperatively and 6-month postoperatively a quality of sexual life questionnaire, the Sexual Health Outcomes in Women Questionnaire (SHOW-Q) and they ranked their symptom intensity using a 10-point visual analogue scale (VAS). Main Outcome Measures. Sexual function was measured through the SHOW-Q scores and pain symptoms through VAS scores. Intraoperative details, type of intervention and perioperative complications were noted. Results. Six months after surgery and postoperative COC treatment, a significant improvement was observed in the SHOW-Q domains of pelvic problem interference, sexual satisfaction and desire (P<0.05). Laparoscopic management of DIE did not change significantly the orgasm area of the sexual functioning (P=0.7). No significant difference was found in SHOW-Q scores between patients submitted to intestinal resection and patients submitted to intestinal nodule excision (P>0.05). Conclusions. Sexual desire, satisfaction with sex and pelvic problem interference with intercourse are significantly improved after 6 months from laparoscopic excision of DIE combined with postoperative COC therapy. No difference in sexual outcomes was detected between patients submitted to intestinal resection and nodule excision.
机译:介绍。深层浸润性子宫内膜异位症(DIE)是一种子宫内膜异位症,其中病变在腹膜表面下穿透5mm以上。这是一种慢性病,会损害女性的性功能。越来越多的证据支持在DIE的管理中进行手术/医学联合治疗。目的本文的目的是评估腹腔镜子宫内膜异位症完全切除和术后联合口服避孕药(COC)给药对DIE患者性功能的影响,并比较接受肠切除和结节切除术的女性的性功能结局。方法。这是一项在三级大学医院中对106名性活跃女性进行的前瞻性队列研究,这些女性经组织学证实为DIE,并通过腹腔镜检查和随后的COC治疗进行了6个月的治疗。患者在术前和术后6个月填写了一份性生活质量问卷,即《女性性健康调查问卷》(SHOW-Q),并使用10点视觉模拟量表(VAS)对症状强度进行了排名。主要观察指标。通过SHOW-Q评分测量性功能,通过VAS评分测量疼痛症状。记录术中细节,干预类型和围手术期并发症。结果。手术和术后COC治疗六个月后,在盆腔问题干扰,性满足感和性欲的SHOW-Q域中观察到了显着改善(P <0.05)。 DIE的腹腔镜治疗并未显着改变性功能的性高潮区域(P = 0.7)。接受肠切除的患者与接受肠结节切除的患者之间的SHOW-Q得分无显着差异(P> 0.05)。结论。腹腔镜切除DIE并结合术后COC治疗6个月后,性欲,性满意度和盆腔问题对性交的干扰显着改善。进行肠切除和结节切除的患者之间未检测到性结果差异。

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