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The Relationships Between Preoperative Sexual Desire and Quality of Life Following Radical Prostatectomy: A 5-Year Follow-Up Study

机译:前列腺癌根治术后术前性欲与生活质量之间的关系:5年随访研究

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Introduction. There were few studies about the relationship between sexual desire (SD) and radical prostatectomy (RP). Aims. We assessed the relationships between RP and quality of life (QOL) according to the preoperative SD. Main Outcome Measure. General QOL was measured with Short Form 36. Sexual function and bother were measured with the University of California, Los Angeles Prostate Cancer Index (PCI). Changes of postoperative SD were also evaluated using PCI. Methods. We analyzed data from 285 men who underwent RP and were prospectively enrolled into a longitudinal cohort study. Patients were divided into two groups according to whether they had SD at baseline, which is addressed in the PCI questionnaire: a low SD (LSD) group and a high SD (HSD) group. The assessments were completed before treatment and 3, 6, 12, 24, and 60 months after RP. Results. Of the 244 men, 52% had high or a fair level of SD before RP, whereas 48% reported that the level of their SD was low. The HSD group reported better sexual function and sexual bother scores than the LSD group at baseline (both P<0.001). Fifty-one percent of the HSD group reported that SD at 3 months was poor or very poor, which did not return to the preoperative level at all postoperative time points. Nearly 20% of the LSD group regained higher SD after RP than the baseline level. The HSD group showed worse sexual bother scores than the baseline throughout the postoperative follow-up (P<0.001). However, the LSD group demonstrated equivalent sexual bother scores after RP compared with the baseline. Conclusions. RP adversely affected SD as well as sexual function and sexual bother. The patients who had HSD experienced greater distress concerning their sexual dysfunction postoperatively than those with LSD.
机译:介绍。关于性欲(SD)与前列腺癌根治术(RP)之间关系的研究很少。目的我们根据术前SD评估了RP和生活质量(QOL)之间的关系。主要结果指标。普通QOL用简短表格36进行测量。性功能和烦恼用加利福尼亚大学洛杉矶分校前列腺癌指数(PCI)进行测量。术后SD的变化也使用PCI进行评估。方法。我们分析了来自285名接受RP的男性的数据,这些男性前瞻性地被纳入了纵向队列研究。根据PCI问卷中的基线是否有SD将患者分为两组:低SD(LSD)组和高SD(HSD)组。评估在治疗前和RP后3、6、12、24和60个月完成。结果。在244名男性中,有52%的人在RP之前的SD水平很高或相当,而48%的人报告其SD水平较低。与基线时的LSD组相比,HSD组报告的性功能和性骚扰评分更好(均P <0.001)。 HSD组中有51%的人报告3个月时的SD差或非常差,在所有术后时间点均未恢复到术前水平。 RP后,近20%的LSD组恢复了比基线水平更高的SD。在整个术后随访中,HSD组的性交困扰评分均较基线差(P <0.001)。然而,与基线相比,LSD组在RP后表现出同等的性骚扰评分。结论。 RP对SD以及性功能和性困扰有不利影响。与LSD患者相比,HSD患者术后性功能障碍的困扰更大。

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