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首页> 外文期刊>The journal of sexual medicine >Optimal Timing to Evaluate Prediagnostic Baseline Erectile Function in Patients Undergoing Robot-Assisted Radical Prostatectomy
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Optimal Timing to Evaluate Prediagnostic Baseline Erectile Function in Patients Undergoing Robot-Assisted Radical Prostatectomy

机译：评估机器人辅助性前列腺癌根治术患者预后基线勃起功能的最佳时机

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Introduction. Accurate assessment of prediagnostic baseline erectile function (EF) is crucial when evaluating postoperative changes of EF in patients undergoing bilateral nerve sparing robot-assisted laparoscopic radical prostatectomy (RLRP). Because score domains of the International Index of Erectile Function-5 (IIEF-5) can be affected by factors such as recall intervals and psychological stress or discomfort due to cancer diagnosis and treatment, it is important to assess the prediagnostic baseline EF at appropriate times. Aim. To determine optimal timing to evaluate prediagnostic baseline EF in patients undergoing bilateral nerve sparing RLRP. Methods. Between March 2009 and February 2010, 54 patients ranging in age from 48 to 74 years were asked to complete IIEF-5 questionnaires before prostate biopsy, 1 day before RLRP, and 1 month after RLRP to assess preoperative baseline EF. Main Outcome Measures. Differences in the mean scores of IIEF-5 were analyzed using paired t-tests. The strengths of the linear relationships among the three IIEF-5 scores were quantified using Pearson's correlation coefficient. An interrator agreement analysis in distribution was performed using the kappa statistic to determine the degree of agreement among the IIEF-5 scores. Results. The mean IIEF-5 score before RLRP was significantly higher than the mean IIEF-5 score before prostate biopsy (P<0.001). There was no significant difference between the mean IIEF-5 scores before prostate biopsy and 1 month following RLRP (P=0.931). Scores of the IIEF-5 taken before prostate biopsy and 1 month following RLRP showed substantial agreement (kappa=0.712), whereas scores of the IIEF-5 taken before prostate biopsy and before RLRP showed lower agreement (kappa=0.325). Conclusion. To more accurately assess the prediagnostic baseline EF in patients with localized prostate cancer, the IIEF-5 questionnaire should be administered before prostate biopsy rather than before RLRP as cancer diagnosis-related symptoms and depression can affect IIEF-5 scores.
机译：介绍。在评估接受双侧神经保留机器人辅助腹腔镜根治性前列腺切除术（RLRP）的患者术后EF的变化时，准确评估诊断前的基线勃起功能（EF）至关重要。由于国际勃起功能指数5（IIEF-5）的得分域可能受诸如回忆间隔，心理压力或由于癌症诊断和治疗引起的不适等因素的影响，因此在适当的时间评估诊断前的基线EF很重要。目标。为了确定评估接受双侧神经保留RLRP的患者的诊断前基线EF的最佳时机。方法。在2009年3月至2010年2月之间，要求54位年龄在48至74岁之间的患者在前列腺穿刺前，RLRP前1天和RLRP后1个月完成IIEF-5问卷调查，以评估术前基线EF。主要观察指标。使用配对t检验分析IIEF-5的平均得分差异。使用皮尔逊相关系数对三个IIEF-5评分之间线性关系的强度进行了量化。使用kappa统计量进行分发者间的一致性分析，以确定IIEF-5得分之间的一致性。结果。 RLRP之前的平均IIEF-5评分显着高于前列腺穿刺活检之前的IIEF-5评分（P <0.001）。前列腺穿刺前和RLRP后1个月的平均IIEF-5评分之间无显着差异（P = 0.931）。前列腺活检之前和RLRP后1个月的IIEF-5评分显示基本一致（kappa = 0.712），而前列腺活检之前和RLRP之前IIEF-5的评分显示较低一致性（kappa = 0.325）。结论。为了更准确地评估局部前列腺癌患者的诊断前基线EF，IIEF-5问卷应在前列腺穿刺前而不是RLRP之前进行，因为与癌症诊断相关的症状和抑郁会影响IIEF-5评分。

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