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首页> 外文期刊>The journal of sexual medicine >Impact of Plasmakinetic Enucleation of the Prostate (PKEP) on Sexual Function: Results of a Prospective Trial
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Impact of Plasmakinetic Enucleation of the Prostate (PKEP) on Sexual Function: Results of a Prospective Trial

机译：前列腺血浆动能成核（PKEP）对性功能的影响：一项前瞻性试验的结果

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Introduction. Recent data have shown that plasmakinetic enucleation of the prostate (PKEP) is a novel and effective procedure for symptomatic benign prostatic hyperplasia (BPH); however, data on patient sexual function after PKEP remain scarce. Aims. This study aims to evaluate the impact of PKEP on sexual function in men with lower urinary tract symptoms because of BPH. Methods. One hundred eighty-six consecutive patients who underwent the PKEP procedure were prospectively enrolled in this study. The International Index of Erectile Function (IIEF-15) and the International Prostate Symptom Score with quality of life scores were completed and compared preoperatively and at 1, 3, 6, and 12 months postoperatively. At each follow-up visit, maximum urinary flow rates, transrectal ultrasound-assessed prostate volume, postvoid residual urine volume, and serum prostate-specific antigen level were also measured and compared with the baseline. Main Outcome Measures. The IIEF global score and its five domains scores were evaluated for each patient, and the Friedman test or chi-square test was used to identify changes from the baseline. Results. There was a slight and nonsignificant increase in the IIEF global score and four of its five domains scores (i.e., erectile function, intercourse satisfaction, sexual desire, and overall satisfaction) at each postoperative assessment (P>0.05 for all). However, a statistically significant reduction was observed in the orgasmic function domain score of IIEF at 3 months (P=0.016), 6 months (P<0.001), and 12 months (P<0.001), respectively, along with the corresponding retrograde ejaculation rates of 48.7%, 49.4%, and 48.8%. Conclusions. PKEP has no negative influence on the quality of erections measured by the self-administered IIEF questionnaire, but it significantly lowers the orgasmic function domain score, reflecting probably postoperative retrograde ejaculation. These findings are important in preoperative counseling of the patients undergoing PKEP for symptomatic BPH.
机译：介绍。最近的数据表明，前列腺的血浆动力学摘除术（PKEP）是一种新的有效的有症状的良性前列腺增生（BPH）的方法。但是，关于PKEP后患者性功能的数据仍然很少。目的这项研究旨在评估PKEP对BPH下泌尿道症状男性的性功能的影响。方法。该研究共纳入了186名接受PKEP手术的患者。术前以及术后1、3、6和12个月完成并比较了国际勃起功能指数（IIEF-15）和国际前列腺症状评分以及生活质量评分。在每次随访中，还测量了最大尿流率，经直肠超声评估的前列腺体积，无尿残留尿量和血清前列腺特异性抗原水平，并将其与基线进行比较。主要观察指标。对每位患者评估IIEF总体评分及其五个领域的评分，并使用Friedman检验或卡方检验来确定基线的变化。结果。每次术后评估时，IIEF总体评分及其五个领域评分中的四个评分（即勃起功能，性交满意度，性欲和总体满意度）均略有增加，但无显着性（所有P均> 0.05）。然而，观察到IIEF的高潮功能域评分分别在3个月（P = 0.016），6个月（P <0.001）和12个月（P <0.001）以及相应的逆行射精方面有统计学意义的降低。率分别为48.7％，49.4％和48.8％。结论。 PKEP对通过自行管理的IIEF问卷测量的勃起质量没有负面影响，但它显着降低了性高潮功能域评分，可能反映了术后逆行射精。这些发现对于接受PKEP的有症状BPH患者的术前咨询很重要。

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