• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>The journal of sexual medicine >Male sexuality and cardiovascular risk. A cohort study in patients with erectile dysfunction.
【24h】

Male sexuality and cardiovascular risk. A cohort study in patients with erectile dysfunction.

机译：男性性行为和心血管风险。勃起功能障碍患者的一项队列研究。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

INTRODUCTION: Although penile blood flow (PBF) has been recommended as an additional diagnostic test in identifying erectile dysfunction (ED) patients at risk for latent cardiovascular disease, no study has ever assessed the possible association of PBF and the relational component of sexual function with incident major cardiovascular events (MACE). AIM: The aim of this study is to investigate whether severity of ED, PBF, and other factors related to a couple's relationship predict incident MACE. METHODS: A consecutive series of 1,687 patients was studied. Different clinical, biochemical, and instrumental (penile flow at color Doppler ultrasound) parameters were evaluated. MAIN OUTCOME MEASURES: Information on MACE was obtained through the City of Florence Registry Office. RESULTS: During a mean follow-up of 4.3 +/- 2.6 years, 139 MACE, 15 of which were fatal, were observed. Cox regression analysis, after adjustment for age and Chronic Disease Score, showed that severe ED predicted MACE (hazard ratio [HR] 1.75; 95% confidence interval 1.10-2.78; P < 0.05). In addition, lower PBF, evaluated both in flaccid (before) and dynamic (after prostaglandin-E1 stimulation) conditions, was associated with an increased risk of MACE (HR = 2.67 [1.42-5.04] and 1.57 [1.01-2.47], respectively, for flaccid [<13 cm/second] and dynamic [<25 cm/second] peak systolic velocity; both P < 0.05). Reported high sexual interest in the partner and low sexual interest in the patient proved to have a protective effect against MACE. CONCLUSIONS: The investigation of male sexuality, and in particular PBF, and sexual desire, could provide insights not only into present cardiovascular status but also into prospective risk.
机译：简介：尽管已建议将阴茎血流（PBF）作为鉴别患有潜在心血管疾病风险的勃起功能障碍（ED）患者的另一项诊断测试，但尚无研究评估PBF与性功能相关成分之间的相关性重大心血管事件（MACE）。目的：本研究的目的是调查ED，PBF的严重程度以及与夫妻关系有关的其他因素是否可预测MACE事件。方法：连续研究了1687例患者。评估了不同的临床，生化和仪器（彩色多普勒超声检查时的血流）参数。主要观察指标：关于MACE的信息是通过佛罗伦萨市登记处获得的。结果：在平均随访4.3 +/- 2.6年期间，观察到139例MACE，其中15例是致命的。在对年龄和慢性病评分进行调整后，Cox回归分析表明，严重的ED可以预测MACE（危险比[HR] 1.75; 95％置信区间1.10-2.78; P <0.05）。此外，在松弛状态（之前）和动态状态（前列腺素E1刺激后）评估的较低的PBF与MACE风险增加相关（HR分别为2.67 [1.42-5.04]和1.57 [1.01-2.47]） ，对于松弛[<13 cm / second]和动态[<25 cm / second]峰值收缩速度;均P <0.05）。事实证明，对伴侣的性兴趣高而对患者的性兴趣低对MACE具有保护作用。结论：对男性性行为，尤其是PBF和性欲的调查，不仅可以提供有关目前心血管状况的信息，还可以提供有关潜在风险的信息。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号