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首页> 外文期刊>The Journal of Thoracic and Cardiovascular Surgery >Development of the American Association for Thoracic Surgery guidelines for low-dose computed tomography scans to screen for lung cancer in North America: Recommendations of the American Association for Thoracic Surgery Task Force for Lung Cancer Screening and Surveillance
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Development of the American Association for Thoracic Surgery guidelines for low-dose computed tomography scans to screen for lung cancer in North America: Recommendations of the American Association for Thoracic Surgery Task Force for Lung Cancer Screening and Surveillance

机译：制定美国胸外科协会的低剂量计算机断层扫描以筛查北美肺癌的指南：美国胸外科协会肺癌筛查和监视工作队的建议

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Objective: The study objective was to establish The American Association for Thoracic Surgery (AATS) lung cancer screening guidelines for clinical practice. Methods: The AATS established the Lung Cancer Screening and Surveillance Task Force with multidisciplinary representation including 4 thoracic surgeons, 4 thoracic radiologists, 4 medical oncologists, 1 pulmonologist, 1 pathologist, and 1 epidemiologist. Members have engaged in interdisciplinary collaborations regarding lung cancer screening and clinical care of patients with, and at risk for, lung cancer. The task force reviewed the literature, including screening trials in the United States and Europe, and discussed local best clinical practices in the United States and Canada on 4 conference calls. A reference library supported the discussions and increased individual study across disciplines. The task force met to review the literature, state of clinical practice, and recommend consensus-based guidelines. Results: Nine of 14 task force members were present at the meeting, and 3 participated by telephone. Two absent task force members were polled afterward. Six unanimous recommendations and supporting work-up algorithms were presented to the Council of the AATS at the 2012 annual meeting in San Francisco, California. Conclusions: Annual lung cancer screening and surveillance with low-dose computed tomography is recommended for smokers and former smokers with a 30 pack-year history of smoking and long-term lung cancer survivors aged 55 to 79 years. Screening may begin at age 50 years with a 20 pack-year history of smoking and additional comorbidity that produces a cumulative risk of developing lung cancer of 5% or greater over the following 5 years. Screening should be undertaken with a subspecialty qualified interdisciplinary team. Patient risk calculator application and intersociety engagement will provide data needed to refine future lung cancer screening guidelines.
机译：目的：该研究目的是建立美国胸外科协会（AATS）肺癌筛查临床实践指南。方法：AATS建立了具有多学科代表的肺癌筛查和监视工作队，包括4名胸外科医生，4名胸放射科医生，4名肿瘤内科医生，1名肺病学家，1名病理学家和1名流行病学家。成员参与了有关肺癌筛查和患有肺癌且有风险的患者的临床护理的跨学科合作。工作队审查了文献，包括在美国和欧洲的筛选试验，并在4个电话会议上讨论了美国和加拿大的当地最佳临床实践。参考图书馆支持讨论并增加了跨学科的个人研究。该工作组开会审查了文献资料，临床实践状况并推荐了基于共识的指南。结果：14个工作队成员中有9人出席了会议，电话参加了3人。随后对两名缺席的特遣部队成员进行了民意调查。在美国加利福尼亚州旧金山举行的2012年年会上，向AATS理事会提出了六项一致的建议和支持的后处理算法。结论：对于那些吸烟史为30包年的吸烟者和曾经吸烟且年龄在55至79岁之间的长期肺癌幸存者，建议每年进行低剂量计算机断层摄影术进行肺癌筛查和监测。筛查可能始于50岁，吸烟史为20包年，并伴有其他合并症，在接下来的5年中，其患肺癌的累积风险为5％或更高。筛选应由具有专业资格的跨学科团队进行。患者风险计算器的应用和社团间的参与将提供完善未来肺癌筛查指南所需的数据。

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