siRNA-MEDIATED INHIBITION OF PHOSPHATIDYLINOSITOL GLYCAN CLASS B (PIGB) CONFERS RESISTANCE TO METHYLMERCURY IN HEK293 CELLS

Gi-Wook HWANG; Tatsuya HAYASHI; Kayoko KITA; Tsutomu TAKAHASHI; Shusuke KUGE; Akira NAGANUMA

首页> 外文期刊>The Journal of toxicological sciences >siRNA-MEDIATED INHIBITION OF PHOSPHATIDYLINOSITOL GLYCAN CLASS B (PIGB) CONFERS RESISTANCE TO METHYLMERCURY IN HEK293 CELLS

【24h】

siRNA-MEDIATED INHIBITION OF PHOSPHATIDYLINOSITOL GLYCAN CLASS B (PIGB) CONFERS RESISTANCE TO METHYLMERCURY IN HEK293 CELLS

机译：siRNA介导的磷脂酰肌醇B类糖皮质激素（PIGB）的抑制作用赋予HEK293细胞甲基汞耐药性

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

We performed functional gene screening, using a siRNA library targeting 8,500 human genes, to identify proteins that are involved in the susceptibility of cells to methylmercury. Screening revealed that downregulation of the gene for phosphatidylinositol glycan class B (PIGB) by siRNA confers resistance to methylmercury in HEK293 cells.

机译：我们使用针对8500个人类基因的siRNA文库进行了功能基因筛选，以鉴定涉及细胞对甲基汞敏感性的蛋白质。筛选显示，siRNA下调磷脂酰肌醇B类（PIGB）基因可赋予HEK293细胞对甲基汞的抗性。

著录项

来源
《The Journal of toxicological sciences》 |2007年第5期|共3页
作者
Gi-Wook HWANG; Tatsuya HAYASHI; Kayoko KITA; Tsutomu TAKAHASHI; Shusuke KUGE; Akira NAGANUMA;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类药学;
关键词
Methylmercury; Resistance; siRNA; PIGB; HEK293 cells;

机译：甲基汞;抗性;siRNA;PIGB;HEK293细胞;

相似文献

外文文献
中文文献
专利

1. siRNA-MEDIATED INHIBITION OF PHOSPHATIDYLINOSITOL GLYCAN CLASS B (PIGB) CONFERS RESISTANCE TO METHYLMERCURY IN HEK293 CELLS [J] . Gi-Wook HWANG, Tatsuya HAYASHI, Kayoko KITA, The Journal of toxicological sciences . 2007,第5期

机译：siRNA介导的磷脂酰肌醇B类糖皮质激素（PIGB）的抑制作用赋予HEK293细胞甲基汞耐药性
2. siRNA-mediated knockdown of the melanocortin 2 receptor accessory protein 2 (MRAP2) gene confers resistance to methylmercury on HEK293 cells. [J] . Hwang GW, Oh SE, Takahashi T, The Journal of toxicological sciences . 2010,第6期

机译：siRNA介导的黑皮质素2受体辅助蛋白2（MRAP2）基因的敲低赋予HEK293细胞对甲基汞的抗性。
3. siRNA-mediated knockdown of the melanocortin 2 receptor accessory protein 2 (MRAP2) gene confers resistance to methylmercury on HEK293 cells [J] . Gi-Wook Hwang, Seong-Eun Oh, Tsutomu Takahashi, The Journal of toxicological sciences . 2010,第6期

机译：siRNA介导的黑皮质素2受体辅助蛋白2（MRAP2）基因敲低赋予HEK293细胞对甲基汞的抗性
4. The a5 GABA_A receptor subunit confers resistance to isoflurane inhibition [C] . B.A. Orser, V.B. Caraiscos, E.K. You-Ten, International Conference on Basic and Systemic Mechanisms of Anesthesia . 2005

机译：A5 Gaba_A受体亚单位赋予异氟醚抑制抗性
5. Inhibition of nucleolar proteins in Caenorhabditis elegans confers enhanced resistance to Salmonella enterica through a p53/cep-1-dependent mechanism [D] . Fuhrman, Laura Elizabeth 2009

机译：秀丽隐杆线虫中核仁蛋白的抑制通过p53 / cep-1依赖性机制增强了对肠沙门氏菌的抗性
6. HAb18G/CD147 cell-cell contacts confer resistance of a HEK293 subpopulation to anoikis in an E-cadherin-dependent manner [O] . Xiao-Kui Ma, Li Wang, Yu Li, 2001

机译：HAb18G / CD147细胞-细胞接触以E-钙粘着蛋白依赖性方式赋予HEK293亚群对失衡的抗性
7. siRNA-MEDIATED INHIBITION OF PHOSPHATIDYLINOSITOL GLYCAN CLASS B (PIGB) CONFERS RESISTANCE TO METHYLMERCURY IN HEK293 CELLS [O] . Gi-Wook HWANG, Tatsuya HAYASHI, Kayoko KITA, 2007

机译：siRNA介导的磷脂酰肌醇聚糖B型B（猪）在HEK293细胞中赋予对甲基汞的抗性
8. Modulation of Pathogenic B Cells through Inhibition of Phosphatidylinositol 3-Kinases. [R] . Stein, P. L. 2016

机译：通过抑制磷脂酰肌醇3-激酶调节致病性B细胞。

siRNA-MEDIATED INHIBITION OF PHOSPHATIDYLINOSITOL GLYCAN CLASS B (PIGB) CONFERS RESISTANCE TO METHYLMERCURY IN HEK293 CELLS

摘要

著录项

相似文献

相关主题

期刊订阅