• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>The Journal of toxicological sciences >An unusual toxic cause of hemolytic-uremic syndrome.
【24h】

An unusual toxic cause of hemolytic-uremic syndrome.

机译：溶血性尿毒症综合征的异常毒性原因。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Hemolytic uremic syndrome (HUS) has been associated with a variety of infective as well as non-infective causes. HUS as a toxic manifestation of exposure to herbicides/pesticides has not been reported so far in literature. We report a subject who presented with clinical features of features of HUS after intentional suicidal ingestion of the herbicidal agent monochloroacetic acid (MCA). A 55-year-old farmer was admitted with a history of consumption of monochloroacetic acid with vomiting, hematochezia and oligo-anuria. Our investigations revealed severe renal failure, metabolic acidosis, anemia, and thrombocytopenia with evidence of intravascular hemolysis. He was treated for HUS with plasma transfusions and haemodialysis in view of renal failure. During the course of hospital admission he developed acute antero-septal myocardial infarction and subsequently succumbed to the disease. MCA is used as an herbicidal agent and also a bleaching agent for silkworm cocoons. The toxicity of MCA has included metabolic acidosis, rhabdomyolysis and renal failure; however HUS has not been described in the literature. Extra -renal manifestations of HUS such as cardiomyopathy have also been infrequently described. This case is presented to highlight an as yet unknown toxicity of MCA.
机译：溶血性尿毒症综合征（HUS）与多种感染性和非感染性原因相关。迄今为止，HUS作为暴露于除草剂/农药的毒性表现尚未在文献中报道。我们报道了一个有意自杀的除草剂一氯乙酸（MCA）表现出HUS特征的临床特征的受试者。一位55岁的农民因呕吐，血便和无尿而食用一氯乙酸的历史被接纳。我们的研究发现严重的肾衰竭，代谢性酸中毒，贫血和血小板减少症，并有血管内溶血的迹象。鉴于肾功能衰竭，他接受了血浆输注和血液透析治疗HUS。在住院期间，他发展为急性前房间隔心肌梗塞，随后死于该病。 MCA用作除草剂，也用作蚕茧的漂白剂。 MCA的毒性包括代谢性酸中毒，横纹肌溶解和肾衰竭。但是，HUS尚未在文献中描述。还很少描述HUS的肾外表现，例如心肌病。呈现这种情况是为了突出MCA的毒性，目前尚不清楚。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号