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首页> 外文期刊>The New England journal of medicine >Antibacterial Prophylaxis in Patients with Cancer and Neutropenia
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Antibacterial Prophylaxis in Patients with Cancer and Neutropenia

机译:癌症和中性粒细胞减少症患者的抗菌预防

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to the editor: The recent studies by Bucaneve et al. and CuIIen et al. (Sept. 8 issue) suggest that many patients with cancer and neutropenia may benefit from levofloxacin prophylaxis. Although the reports were published in tandem, their clinical implications differ fundamentally. Bucaneve etal. targeted "high-risk" patients (stem-cell transplant recipients or patients with leukemia) with anticipated neutropenia lasting more than seven days, a previously accepted approach.3 In contrast, most patients studied by Cullen et al. had solid tumors. Because patients with such tumors are unlikely to have prolonged or profound neutropenia, they are at lower risk for infectious complications.
机译:致编辑:Bucaneve等人的最新研究。和CuIIen等。 (9月8日发行)表明,许多患有癌症和中性粒细胞减少症的患者可能会受益于左氧氟沙星预防。尽管这些报告是串联发表的,但是它们的临床意义却有着根本的不同。 Bucaneve等。针对的是预期接受的中性粒细胞减少症持续超过7天的“高危”患者(干细胞移植受者或白血病患者),这是先前公认的方法。3相反,Cullen等人研究的大多数患者。有实体瘤。由于患有此类肿瘤的患者不太可能患有长期或严重的中性粒细胞减少症,因此感染并发症的风险较低。

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