首页> 外文期刊>The journals of gerontology.Series A. Biological sciences and medical sciences >Selective atrophy of left hemisphere and frontal lobe of the brain in old men.
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Selective atrophy of left hemisphere and frontal lobe of the brain in old men.

机译:老年人左半球和大脑额叶的选择性萎缩。

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摘要

In this study, volumes of the whole brain, hemispheres, and frontal lobes of young and elderly adults were quantified by an automated method. Effects of age, sex, and side on absolute and relative volumes of the brain structures were evaluated. Compared with the young group, elderly participants showed a 15% volume loss in the whole brain and hemispheres, and a 22% volume loss in the frontal lobes. The relative volume of the left hemisphere in the elderly group decreased more than that of the right hemisphere. Elderly men showed significantly greater left hemisphere and left frontal lobe volume losses than did elderly women, indicating that the larger left hemisphere relative volume reduction is largely contributed to by selective atrophy of the left frontal lobe volume in elderly men. These results may reflect age- and sex-related functional deterioration in the left brain.
机译:在这项研究中,年轻人和老年人的全脑,半球和额叶的体积通过自动化方法进行了量化。评估了年龄,性别和侧面对大脑结构的绝对和相对体积的影响。与年轻组相比,老年参与者的全脑和半球体积减少了15%,额叶体积减少了22%。老年人组左半球的相对体积比右半球的体积下降更多。老年男性比老年女性表现出明显更大的左半球和左额叶体积损失,这表明较大的左半球相对体积减少主要是由于老年男性左额叶体积选择性萎缩所致。这些结果可能反映了左脑中与年龄和性别相关的功能恶化。

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