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首页> 外文期刊>The journals of gerontology.Series A. Biological sciences and medical sciences >A prospective study of gait performance and subsequent cognitive decline in a general population of older Japanese.
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A prospective study of gait performance and subsequent cognitive decline in a general population of older Japanese.

机译:对日本老年人群中步态表现和随后的认知能力下降的前瞻性研究。

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Gait speed is a good predictor of cognitive decline in later life. However, it is not known whether step length or step frequency is better for predicting such decline. This study aimed to compare the predictive value for cognitive decline of gait performance measures in a population of older Japanese.Among 853 cognitively intact adults aged 70 years or older who participated in a baseline survey, 666 (mean age, 75.5 [SD 4.4] years; women, 59.3%) were reevaluated at least once during the subsequent 4-year period. Cognition was assessed by Mini-Mental State Examination (MMSE), and cognitive decline was defined as a decrease of three points or more on the Mini-Mental State Examination during follow-up.During a median follow-up of 2.7 years, 110 adults (16.5%) had cognitive decline. Among the measures of gait performance (speed, step length, and frequency), step length was the most predictive of cognitive decline. After controlling for important confounders, older men in the lowest and middle tertiles of step length at maximum speed and older women in the lowest and middle tertiles of step length at usual speed were 4.42 (95% confidence interval: 1.65-11.8), 2.17 (0.82-5.71), 5.76 (2.15-15.4), and 2.44 (0.94-6.35) times as likely to develop cognitive decline, respectively, as those of the same sex and walking speed who were in the highest tertile.Step length was an independent predictor of cognitive decline in a general population of older adults and may be a better predictor than overall gait speed of such decline.
机译:步态速度可以很好地预测以后生活中认知能力的下降。但是,尚不清楚步长或步频对于预测这种下降是否更好。这项研究旨在比较年龄较大的日本人群对步态表现认知下降的预测价值。参加基线调查的853名年龄在70岁以上的完好无损的成年人中,有666名(平均年龄为75.5 [SD 4.4]岁) ;女性(59.3%)在接下来的4年中至少进行了一次重新评估。认知水平通过小精神状态检查(MMSE)进行评估,认知能力下降的定义为随访期间小精神状态检查下降3分或更多。在2.7年的中位随访期间,有110名成年人(16.5%)的认知能力下降。在步态表现的度量(速度,步长和频率)中,步长最能预测认知能力下降。在控制了重要的混杂因素后,以最快速度在最低和中等三分位数的步长男性和以正常速度在最低和中等三分位数的步长男性分别为4.42(95%置信区间:1.65-11.8),2.17(认知能力下降的几率分别是同性和步行速度最高的三分之二的人的0.82-5.71),5.76(2.15-15.4)和2.44(0.94-6.35)的两倍。步长是独立的一般老年人认知能力下降的预测因素,并且比这种下降的总体步态速度更好。

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