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首页> 外文期刊>The journals of gerontology.Series A. Biological sciences and medical sciences >A prospective study of gait performance and subsequent cognitive decline in a general population of older Japanese.
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A prospective study of gait performance and subsequent cognitive decline in a general population of older Japanese.

机译:日本众年人口一般人群步态绩效及随后的认知下降的前瞻性研究。

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Gait speed is a good predictor of cognitive decline in later life. However, it is not known whether step length or step frequency is better for predicting such decline. This study aimed to compare the predictive value for cognitive decline of gait performance measures in a population of older Japanese.Among 853 cognitively intact adults aged 70 years or older who participated in a baseline survey, 666 (mean age, 75.5 [SD 4.4] years; women, 59.3%) were reevaluated at least once during the subsequent 4-year period. Cognition was assessed by Mini-Mental State Examination (MMSE), and cognitive decline was defined as a decrease of three points or more on the Mini-Mental State Examination during follow-up.During a median follow-up of 2.7 years, 110 adults (16.5%) had cognitive decline. Among the measures of gait performance (speed, step length, and frequency), step length was the most predictive of cognitive decline. After controlling for important confounders, older men in the lowest and middle tertiles of step length at maximum speed and older women in the lowest and middle tertiles of step length at usual speed were 4.42 (95% confidence interval: 1.65-11.8), 2.17 (0.82-5.71), 5.76 (2.15-15.4), and 2.44 (0.94-6.35) times as likely to develop cognitive decline, respectively, as those of the same sex and walking speed who were in the highest tertile.Step length was an independent predictor of cognitive decline in a general population of older adults and may be a better predictor than overall gait speed of such decline.
机译:步态速度是后期生命中的认知下降的良好预测因素。然而,尚不知道步长或步进频率是否更好地预测这种下降。本研究旨在比较老年日龄人口步态绩效措施的认知性能下降的预测价值.AMONG 853认知完整的成年人参加了70岁或以上的成年人,他们参加了基线调查,666(平均年龄,75.5 [SD 4.4]年;在随后的4年期间,女性59.3%)至少重新评估一次。通过迷你精神状态检查(MMSE)评估认知,并且认知下降被定义为在随访期间迷你精神状态检查的三点或更长的减少。持续27岁的中位随访,110名成年人(16.5%)认知下降。在步态性能(速度,步长和频率)的措施中,步长是最可预测的认知下降。在控制重要的混淆后,在常规速度最高和中间速度的最大速度和老年妇女的最低和中间妇女中最低和中间三分之一的男性为4.42(95%置信区间:1.65-11.8),2.17( 0.82-5.71),5.76(2.15-15.4)和2.44(0.94-6.35)分别产生认知下降的可能性,因为那些在最高的Tertile.step长度中的相同性和步行速度的速度是一个独立的高龄成年人一般人群认知下降的预测因子,可能是比这种衰退的整体步态速度更好的预测因子。

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