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首页> 外文期刊>The journals of gerontology.Series A. Biological sciences and medical sciences >Occurrence of Hypotension in Older Participants. Which 24-hour ABPM Parameter Better Correlate With?
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Occurrence of Hypotension in Older Participants. Which 24-hour ABPM Parameter Better Correlate With?

机译:老年参与者发生低血压。哪个24小时ABPM参数更适合?

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Objectives. The aim of the present study was to investigate the prevalence of hypotension in older participants and to identify which 24-hour ambulatory blood pressure monitoring parameter better correlated with the occurrence of hypotension.We studied 588 elderly participants (mean age 78.7 ± 7.1 years; 70% women) who underwent a 24-hour ambulatory blood pressure (BP) monitoring, without moderate-to-severe cognitive impairment, myocardial infarction, or stroke within the previous 6 months; renal (serum creatinine > 2.5 mg/dL), respiratory, or liver insufficiency; and atrial fibrillation.In older participants, the occurrence of systolic hypotension is very common (≈55% presenting at least one episode of systolic blood pressure (SBP) < 100 mmHg and about 20% presenting ≥10% of the SBP registrations < 100 mmHg). More than 30% of participants with 24-hour SBP, daytime, and nighttime above the reference threshold had hypotension. Hypotension did not correlated with BP variability indices (standard deviation of BPs). None of the parameters commonly present in 24-hour ambulatory BP monitoring clinical reports is able to accurately identify those older participants with episode of hypotension.Episodes of SBP hypotension are extremely common in older participants and do not appear to relate to BP variability indices. Indeed, no parameter of 24-hour ambulatory BP monitoring was capable to accurately identify the occurrence of hypotension. We expect that ongoing studies will contribute to identification of specific factors predicting hypotensive episodes in the older participants.
机译:目标。本研究的目的是调查老年参与者的低血压患病率,并确定哪种24小时动态血压监测参数与低血压的发生更好地相关。我们研究了588名老年参与者(平均年龄78.7±7.1岁; 70) %的女性)在过去6个月内进行了24小时动态血压(BP)监测,而没有中度至重度认知障碍,心肌梗塞或中风;肾脏(血清肌酐> 2.5 mg / dL),呼吸道或肝功能不全;在年龄较大的参与者中,收缩期低血压的发生非常普遍(≈55%表示至少发生一次收缩压(SBP)<100 mmHg,约20%表示≥10%的SBP记录<100 mmHg )。超过30%的24小时SBP,白天和夜间高于参考阈值的参与者患有低血压。低血压与血压变异性指数(血压标准差)无关。 24小时门诊BP监测临床报告中通常没有任何参数能够准确识别出患有低血压事件的老年参与者.SBP低血压的发作在老年参与者中极为常见,并且似乎与BP变异性指数无关。确实,没有24小时动态BP监测参数能够准确识别低血压的发生。我们希望正在进行的研究将有助于识别预测老年参与者降血压发作的特定因素。

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