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首页> 外文期刊>The journals of gerontology.Series A. Biological sciences and medical sciences >Occurrence of Hypotension in Older Participants. Which 24-hour ABPM Parameter Better Correlate With?
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Occurrence of Hypotension in Older Participants. Which 24-hour ABPM Parameter Better Correlate With?

机译:老年参与者中的低血压发生。 哪24小时ABPM参数更好地相关?

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Objectives. The aim of the present study was to investigate the prevalence of hypotension in older participants and to identify which 24-hour ambulatory blood pressure monitoring parameter better correlated with the occurrence of hypotension.We studied 588 elderly participants (mean age 78.7 ± 7.1 years; 70% women) who underwent a 24-hour ambulatory blood pressure (BP) monitoring, without moderate-to-severe cognitive impairment, myocardial infarction, or stroke within the previous 6 months; renal (serum creatinine > 2.5 mg/dL), respiratory, or liver insufficiency; and atrial fibrillation.In older participants, the occurrence of systolic hypotension is very common (≈55% presenting at least one episode of systolic blood pressure (SBP) < 100 mmHg and about 20% presenting ≥10% of the SBP registrations < 100 mmHg). More than 30% of participants with 24-hour SBP, daytime, and nighttime above the reference threshold had hypotension. Hypotension did not correlated with BP variability indices (standard deviation of BPs). None of the parameters commonly present in 24-hour ambulatory BP monitoring clinical reports is able to accurately identify those older participants with episode of hypotension.Episodes of SBP hypotension are extremely common in older participants and do not appear to relate to BP variability indices. Indeed, no parameter of 24-hour ambulatory BP monitoring was capable to accurately identify the occurrence of hypotension. We expect that ongoing studies will contribute to identification of specific factors predicting hypotensive episodes in the older participants.
机译:目标。本研究的目的是探讨较旧的参与者中低血压的患病率,并确定与肺部发生的发生更好的24小时动态血压监测参数。我们研究了588名老年人参与者(平均年龄78.7±7.1岁; 70 %妇女经历了24小时的动态血压(BP)监测,没有中度至严重的认知障碍,心肌梗死或前6个月内的卒中;肾(血清肌酐> 2.5mg / dL),呼吸或肝功能不足;和心房颤动。在较旧的参与者中,收缩性低血压的发生是非常常见的(≈55%呈现至少一种收缩压(SBP)<100 mmHg的发作,≥10%的SBP注册<100 mmHg )。超过30%的参与者,参考阈值高于24小时SBP,白天和夜间的参考阈值具有低血压。低血压与BP可变性指数没有相关(BPS的标准偏差)。 24小时动态BP监测临床报告中常用的参数均不能准确地识别具有SBP低血压的剧集中的那些较旧的参与者在旧的参与者中非常常见,并且似乎与BP变异指数没有涉及。实际上,没有24小时动态BP监测的参数能够准确识别低血压的发生。我们预计正在进行的研究将有助于识别预测老年参与者中的低位集的特定因素。

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