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首页> 外文期刊>The journals of gerontology.Series A. Biological sciences and medical sciences >Number of teeth and mortality risk in the Baltimore Longitudinal Study of Aging.
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Number of teeth and mortality risk in the Baltimore Longitudinal Study of Aging.

机译：巴尔的摩纵向老龄化研究中的牙齿数量和死亡风险。

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BACKGROUND: Findings from several studies suggested an association between oral health and several health outcomes including cardiovascular disease, aspiration pneumonia, malnutrition, poor quality of life, and mortality. Using data from the Baltimore Longitudinal Study of Aging (BLSA), we tested the hypothesis that number of teeth is indicative of mortality risk independent of other confounders. METHODS: Dentists conducted a standardized oral examination that included tooth count, tooth with coronal and cervical caries count, and gingival and periodontal index. Blood tests used in the analysis included fasting glucose, oral glucose tolerance test, serum low-density lipoprotein (LDL), high-density lipoprotein (HDL) cholesterol, triglycerides, and white blood cell counts. Physical activity, skin fold thickness, body mass index and chronic diseases were also evaluated. RESULTS: Of the 500 BLSA participants evaluated, 198 died an average of 130 (+/-75) months postdental evaluation, and 302 survivors were followed for a mean of 185 (+/-90) months. Based on multivariate Cox regression models, being edentulous or having than 20 teeth was independently associated with mortality. CONCLUSION: The results of this study support the notion that number of teeth is a significant and independent risk indicator for early mortality. These findings suggest that the improvement of oral health may have a positive impact on general health and may delay mortality.
机译：背景：多项研究的结果表明，口腔健康与包括心血管疾病，吸入性肺炎，营养不良，生活质量差和死亡率在内的多种健康状况之间存在关联。使用来自巴尔的摩老龄化纵向研究（BLSA）的数据，我们检验了牙齿数量独立于其他混杂因素的死亡风险指示这一假设。方法：牙医进行了标准化的口腔检查，包括牙齿计数，具有冠状和子宫颈龋齿的牙齿以及牙龈和牙周指数。分析中使用的血液测试包括空腹血糖，口服葡萄糖耐量测试，血清低密度脂蛋白（LDL），高密度脂蛋白（HDL）胆固醇，甘油三酸酯和白细胞计数。还评估了身体活动，皮肤褶皱厚度，体重指数和慢性疾病。结果：在评估的500名BLSA参与者中，有198名死者平均在牙科评估后130（+/- 75）个月内死亡，并且对302名幸存者进行了平均185（+/- 90）个月的随访。根据多元Cox回归模型，无牙或牙齿少于20个与死亡率独立相关。结论：这项研究的结果支持以下观点：牙齿数量是早期死亡的重要且独立的危险指标。这些发现表明，口腔健康的改善可能对总体健康产生积极影响，并可能延迟死亡率。

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