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首页> 外文期刊>The journals of gerontology.Series A. Biological sciences and medical sciences >The association between the body mass index and 4-year all-cause mortality in older hospitalized patients.
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The association between the body mass index and 4-year all-cause mortality in older hospitalized patients.

机译：老年住院患者的体重指数与4年全因死亡率之间的关联。

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Association between body mass index (BMI) and long-term mortality is poorly studied in older hospitalized populations.The researchers prospectively studied the impact of the BMI, comorbidities, and malnutrition on long-term mortality in 444 patients (mean age 85.3±6.7 years; 74.0% women) receiving geriatric inpatient care. All-cause mortality was determined using simple and multiple Cox proportional hazard models.Higher BMI was associated with a higher prevalence of diabetes, hypertension, and heart failure, but with a lower prevalence of malignancies. Four-year all-cause mortality was inversely associated with a BMI greater than or equal to 30kg/m(2) (hazard ratio = 0.59, p = .037) and positively associated with age, male gender, several individual comorbidities, and the global disease load determined by the Cumulative Illness Rating scale. The inverse association between a BMI greater than or equal to 30 and mortality remained significant after adjustment for age, gender, smoking, individual comorbidities (including heart failure and malignancies), Cumulative Illness Rating scale scores, and malnutrition parameters (hazard ratio = 0.52, p = .015). One-year mortality was associated with the Cumulative Illness Rating scale score but not with BMI categories. There were no survival differences between patients in low (<20.0) and intermediate (20.0-24.9 and 25.0-29.9) BMI categories.A BMI greater than or equal to 30 is associated with better long-term survival in hospitalized older patients, even after extensive adjustment for comorbidities, malnutrition, and smoking. Conversely, a low BMI (<20-25) is not associated with excess mortality, likely due to the overriding impact of multiple comorbidities. The researchers' observations have important implications for the mortality risk stratification in older high-risk patients.
机译：在老年住院人群中，体重指数（BMI）与长期死亡率之间的关联研究很少，研究人员前瞻性地研究了444名患者（平均年龄85.3±6.7岁）中BMI，合并症和营养不良对长期死亡率的影响; 74.0％的女性）接受老年病住院治疗。全因死亡率是通过简单和多种Cox比例风险模型确定的.BMI越高与糖尿病，高血压和心力衰竭的患病率越高，但恶性肿瘤的患病率越低。四年全因死亡率与BMI大于或等于30kg / m（2）呈负相关（危险比= 0.59，p = .037），与年龄，男性，若干个人合并症和累积疾病等级量表确定的全球疾病负担。在调整了年龄，性别，吸烟，个体合并症（包括心力衰竭和恶性肿瘤），累积疾病等级量表评分和营养不良参数（危害比= 0.52， p = .015）。一年死亡率与累积疾病评估量表评分相关，但与BMI类别无关。低（<20.0）和中（20.0-24.9和25.0-29.9）BMI类别的患者之间没有生存差异.BMI大于或等于30与住院老年患者的更好长期生存相关，即使在对合并症，营养不良和吸烟进行了广泛的调整。相反，低BMI（<20-25）与过多的死亡率无关，这可能是由于多种合并症的压倒性影响所致。研究人员的观察结果对老年高危患者的死亡风险分层具有重要意义。

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