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Treatment of Parkinson hypophonia with percutaneous collagen augmentation.

机译:经皮胶原蛋白增强治疗帕金森性低音。

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摘要

OBJECTIVES: It has been estimated that more than 70% of patients with Parkinson disease experience voice and speech disorders characterized by weak and breathy phonation, and dysarthria. This study reports on the efficacy of treating Parkinson patients who have glottal insufficiency. STUDY DESIGN AND METHODS: Thirty-five patients underwent collagen augmentation of the vocal folds for hypophonia associated with Parkinson disease, using a new technique of percutaneous injection with fiberoptic guidance. Patient response to the collagen augmentation was determined by telephone survey. RESULTS AND CONCLUSIONS: The procedure required minimal patient participation and was safely performed on all the patients who were studied. Results of the survey indicated that 75% of patient responses demonstrated satisfaction with the technique, compared with 16% of patient ratings reflecting dissatisfaction. These results were moderately correlated with the duration of improvement of the dysphonia. Results of this preliminary evaluation demonstrate that voice deficits in Parkinson disease are amenable to vocal fold augmentation. Because this procedure requires minimal patient participation and can be safely performed in an office setting, it may also be useful in other severely debilitating neuromotor diseases that result in glottal insufficiency and hypophonia.
机译:目的:据估计,超过70%的帕金森病患者会经历语音和言语障碍,其特征是呼吸声弱,呼吸困难和构音障碍。这项研究报告了治疗声门关闭不全的帕金森病患者的疗效。研究设计和方法:35名患者使用一种新的经皮光纤引导注射技术,对与帕金森氏病相关的低音症进行了声带胶原蛋白增强。通过电话调查确定患者对胶原蛋白增加的反应。结果与结论:该程序需要最少的患者参与,并且对所有接受研究的患者均安全进行。调查结果表明,有75%的患者对此技术表示满意,而有16%的患者对不满意表示满意。这些结果与发声障碍改善的持续时间适度相关。这项初步评估的结果表明,帕金森氏病中的声音缺陷适合进行声带增强。因为此过程需要最少的患者参与,并且可以在办公室环境中安全地执行,所以它在其他严重衰弱的神经运动疾病(会导致声门功能不全和低音)中也很有用。

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