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首页> 外文期刊>The Laryngoscope: A Medical Journal for Clinical and Research Contributions in Otolaryngology, Head and Neck Medicine and Surgery, Facial Plastic and Reconstructive Surgery .. >Profound hearing loss attributable to cochlear nerve disease: diagnosis with combination of otoacoustic emission and magnetic resonance imaging.
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Profound hearing loss attributable to cochlear nerve disease: diagnosis with combination of otoacoustic emission and magnetic resonance imaging.

机译：可归因于耳蜗神经疾病的严重听力损失：结合耳声发射和磁共振成像进行诊断。

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OBJECTIVE: To detect the causes of deafness based on the combined findings of auditory brainstem response (ABR), distortion product otoacoustic emissions (DPOAEs), and three-dimensional Fourier transformation-constructive interference in steady state (3DFT-CISS) magnetic resonance imaging (MRI). STUDY DESIGN: Retrospective review of the medical records of 13 patients with unilateral profound hearing loss since childhood. METHODS: Subjects were tested with pure-tone audiometry, ABR, DPOAEs, and 3DFT-CISS imaging. RESULTS: No significant components of ABR were observable in any of the deaf ears. In 10 cases, the cochlear nerves of the deaf ears were found to be as normal as the healthy sides by 3DFT-CISS imaging, and no significant levels of DPOAEs were recorded. In the other three cases, no apparent cochlear nerves were identified by 3DFT-CISS imaging. Although no significant levels of DPOAEs were observable in two cases with cochlear nerves invisible by the MRI study, almost the same level of DPOAEs as that in the healthy side was recorded in the last case. CONCLUSIONS: In the last particular case, the cochlear nerve seemed to be mainly responsible for the profound deafness. 3DFT-CISS imaging in combination with preexisting audiological measures may provide direct evidence for the cochlear nerve disease. steady state, internal auditory canal, cochlear nerve disease.
机译：目的：根据听觉脑干反应（ABR），畸变产物耳声发射（DPOAEs）和稳态（3DFT-CISS）三维傅立叶变换-建设性干扰（3DFT-CISS）磁共振成像的综合发现来检测耳聋的原因（ MRI）。研究设计：回顾性分析13例自童年以来单侧严重听力损失的患者的病历。方法：用纯音测听，ABR，DPOAEs和3DFT-CISS成像对受试者进行测试。结果：在任何聋耳中均未观察到明显的ABR成分。在10例病例中，通过3DFT-CISS成像发现充耳聋的耳蜗神经与健康侧正常，并且未记录到明显的DPOAEs水平。在其他三例中，通过3DFT-CISS成像未发现明显的耳蜗神经。尽管在MRI研究中看不到耳蜗神经的2例病例中均未观察到明显的DPOAEs水平，但在最后一例中记录的DPOAEs水平与健康侧几乎相同。结论：在最后一个特定病例中，耳蜗神经似乎是导致严重耳聋的主要原因。 3DFT-CISS成像结合预先存在的听力学措施可能会为耳蜗神经疾病提供直接证据。稳定状态，内听道，耳蜗神经疾病。

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