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首页> 外文期刊>The Laryngoscope: A Medical Journal for Clinical and Research Contributions in Otolaryngology, Head and Neck Medicine and Surgery, Facial Plastic and Reconstructive Surgery .. >Rathke cleft cyst: diagnostic and therapeutic considerations.
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Rathke cleft cyst: diagnostic and therapeutic considerations.

机译：Rathke裂囊肿：诊断和治疗考虑。

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OBJECTIVE To highlight diagnostic and therapeutic issues about Rathke cleft cysts for otorhinolaryngologists.STUDY DESIGN Retrospective.METHODS We retrospectively reviewed data collected on Rathke cleft cysts between 1978 and 1998: presenting symptoms, visual acuity, surgical treatment, complications, recurrences, and effect on daily activity.RESULTS Twenty-nine patients were diagnosed with a Rathke cleft cyst (11 male and 18 female patients; mean age, 46 y). The most common presenting symptom was head pain (55%). The majority (59%) of cases demonstrated suprasellar extension on preoperative imaging, with pituitary dysfunction identified in 66%. Recurrence occurred in eight patients (28%). Postoperative visual function improved or remained stable in all patients. Persistent pituitary dysfunction required hormonal supplementation in seven patients (24%). Only one patient with an astrocytoma in addition to a Rathke cleft cyst did not maintain the ability to perform normally on an assessment of activities of daily living, a striking contrast to patients with craniopharyngioma.CONCLUSIONS Conclusions were as follows: 1) Rathke cleft cysts must be considered as sources of head pain and pituitary dysfunction. 2) Persistent or recurrent cyst formation occurs in approximately one-third of the patients. Recurrence may take many years, and follow-up imaging is recommended for at least a decade. 3) Maintenance of the ability to perform the activities of normal daily living can be expected after surgical management. 4) Most Rathke cleft cysts can be managed through transnasal exposure of the sella. 5) Packing the sella may result in predisposition to recurrent cyst formation.
机译：目的为耳鼻喉科医生强调有关Rathke c裂囊肿的诊断和治疗问题。研究设计回顾性方法我们回顾性回顾了1978年至1998年间收集的有关Rathke c裂囊肿的数据：表现出症状，视力，手术治疗，并发症，复发以及对日常的影响结果：29例患者被诊断患有Rathke裂囊肿（男11例，女18例;平均年龄46岁）。最常见的症状是头痛（55％）。多数病例（59％）在术前影像学表现为鞍上扩展，其中66％发现垂体功能障碍。 8例患者（28％）复发。所有患者术后视觉功能改善或保持稳定。持续性垂体功能障碍需要补充7名患者的激素（24％）。结论：结论：1）Rathke裂隙性囊肿必须除Rathke裂隙性囊肿以外的星形细胞瘤患者的日常生活活动能力维持正常，这与颅咽管瘤患者形成鲜明对比。被认为是头痛和垂体功能障碍的根源。 2）约有三分之一的患者发生持续性或复发性囊肿形成。复发可能需要很多年，建议至少进行十年随访。 3）进行外科手术治疗后，可以维持正常的日常生活活动能力。 4）大多数Rathke裂口囊肿可以通过鼻腔的鼻腔暴露进行处理。 5）包装蝶鞍可能导致易发性囊肿形成。

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