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首页> 外文期刊>The Laryngoscope: A Medical Journal for Clinical and Research Contributions in Otolaryngology, Head and Neck Medicine and Surgery, Facial Plastic and Reconstructive Surgery .. >Comparative study of cochlear damage with three perimodiolar electrode designs.
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Comparative study of cochlear damage with three perimodiolar electrode designs.

机译：三种perimodiolar电极设计对耳蜗损伤的比较研究。

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摘要

OBJECTIVE: To describe intracochlear insertion trauma caused by three perimodiolar cochlear implant electrodes. STUDY DESIGN: Descriptive histological study of 15 human cadaver temporal bones. METHODS: Fifteen cadaver temporal bones underwent surface preparation and were implanted with one of the following perimodiolar electrode arrays: Combi 40+PM (MedEl Corporation), HiFocus II (Advanced Bionics Corporation), or Contour (Cochlear Corporation). A cryosectioning technique was used to study horizontal sections at 200 microm intervals with the electrode in place. Image-enhanced videofluoroscopy and computer-assisted morphometrics were used to assess the mechanism of insertion trauma and to determine electrode position within the modiolus. RESULTS: Histological examination revealed varying degrees of damage to the spiral ligament, basilar membrane, and osseous spiral lamina. Using a novel grading system for electrode trauma, there was no statistically significant difference among the three electrodes. A literature search of histological studies of a commonly used "standard" electrode showed damage equal to or greater than that seen in the current study. CONCLUSIONS: Insertion trauma caused by periomodiolar electrodes occurs to an acceptable degree. Refinement of electrodes based on mechanisms of trauma may be able to further reduce damage.
机译：目的：描述由三个imo旁蜗人工耳植入电极引起的耳蜗内插入创伤。研究设计：对15个人尸体颞骨的描述性组织学研究。方法：对15具尸体颞骨进行表面处理，并植入以下perimodiolar电极阵列之一：Combi 40 + PM（MedEl公司），HiFocus II（Advanced Bionics公司）或Contour（Cochlear公司）。使用冷冻切片技术在电极就位的情况下以200微米的间隔研究水平切片。图像增强型电子荧光检查法和计算机辅助形态计量学用于评估插入创伤的机制，并确定电极在阴茎内的位置。结果：组织学检查发现螺旋韧带，基底膜和骨螺旋层受到不同程度的损伤。使用新型的电极创伤分级系统，三个电极之间没有统计学上的显着差异。文献中对常用“标准”电极的组织学研究发现，其损伤等于或大于当前研究中的损伤。结论：由椎弓根电极引起的插入创伤发生在可接受的程度。基于创伤机理的电极细化可以进一步减少损伤。

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