...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>The Laryngoscope: A Medical Journal for Clinical and Research Contributions in Otolaryngology, Head and Neck Medicine and Surgery, Facial Plastic and Reconstructive Surgery .. >111Indium pentetreotide scan detection of familial paragangliomas.
【24h】

111Indium pentetreotide scan detection of familial paragangliomas.

机译：111戊四肽铟扫描检测家族性神经节瘤。

获取原文
获取原文并翻译 | 示例
   

获取外文期刊封面封底 >>

       
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Approximately 10% of head and neck paragangliomas are familial. Magnetic resonance imaging (MRI) is reported to be the best method for screening these families. 111Indium pentetreotide (Octreoscan) scintigraphy has been shown to be a sensitive indicator of neural crest tumors such as paragangliomas. Early diagnosis and treatment of familial paragangliomas (FP) would decrease the morbidity of tumor excision. Patients from two kindred with FP were scanned 24 hours after intravenous injection with approximately 6 millicuries of 111Indium pentetreotide. The entire body was imaged. Areas of increased uptake were further imaged with MRI. Altogether, five patients had positive 111Indium pentetreotide scans. Two unsuspected glomus tympanicums and bilateral carotid body tumors were identified. Three people tested had no abnormal uptake. There were no untoward reactions to the nuclide. 111Indium pentetreotide scanning is a safe, noninvasive method for early diagnosis of FP and is useful in detecting multicentric lesions. Patients suspect for FP are undergoing 111Indium pentetreotide imaging and followed up with MRI of the involved site if positive.
机译：头颈部神经节瘤约有10％是家族性的。据报道，磁共振成像（MRI）是筛查这些家族的最佳方法。 111戊四醇铟（Octreoscan）闪烁显像已被证明是神经波谷瘤（如神经节瘤）的敏感指标。家族性神经节瘤（FP）的早期诊断和治疗将降低肿瘤切除的发病率。静脉注射后，来自两个家族的FP患者在静脉注射后24小时接受了大约6毫厘升的111铟五肽的扫描。整个身体都成像了。摄取更多的区域用MRI进一步成像。总共有5名患者的111In戊四肽铟扫描阳性。鉴定出了两个未曾怀疑的鼓膜球虫和双侧颈动脉体瘤。测试的三人没有异常摄取。对核素没有不良反应。 111戊四醇铟扫描是一种早期诊断FP的安全，无创方法，可用于检测多中心病变。怀疑患有FP的患者正在接受111铟戊四肽影像学检查，如果阳性，则对受累部位进行MRI随访。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号