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Differential diagnosis of adductor spasmodic dysphonia and muscle tension dysphonia using phonatory break analysis.

机译:通过发声断裂分析鉴别诊断内收肌痉挛性肌张力障碍和肌张力性肌张力障碍。

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摘要

OBJECTIVES: Muscle tension dysphonia (MTD) can masquerade as adductor spasmodic dysphonia (ADSD) leading to diagnostic confusion. Intraword phonatory breaks have been offered as the sine qua non of ADSD, however, little is known regarding the presence of phonatory breaks in MTD. This investigation assessed the diagnostic worth of acoustic analysis of phonatory breaks as a possible objective test to distinguish ADSD from MTD. STUDY DESIGN: Case-control comparison. METHODS: Voice samples from patients with confirmed ADSD (n = 41) and MTD (n = 59) were analyzed acoustically to determine the presence, frequency, and duration of phonatory breaks -- defined as complete interruption of phonation within a word. Estimates of sensitivity, specificity, positive and negative predictive value, and likelihood ratios were calculated to determine the precision and worth of phonatory break analysis as a clinical diagnostic test. RESULTS: 1) Individuals with ADSD showed a significantly higher number of phonatory breaks as compared with MTD. 2) All measures of diagnostic precision varied according to both duration and frequency of phonatory breaks, with separation of males and females leading to different diagnostic test performance results. CONCLUSIONS: The results suggest that phonatory break analysis offers promise as an objective test to distinguish ADSD from MTD, with respectable diagnostic precision, especially among men. Automation of the acoustic analysis procedure should be explored.
机译:目的:肌张力障碍(MTD)会伪装成内收肌痉挛性障碍(ADSD),导致诊断混乱。字内语音中断已被提供为ADSD的必要条件,但是,关于MTD中语音中断的存在知之甚少。这项研究评估了发声中断的声学分析的诊断价值,作为将ADSD与MTD区分的可能的客观测试。研究设计:病例对照比较。方法:对经过确认的ADSD(n = 41)和MTD(n = 59)患者的语音样本进行声学分析,以确定发声中断的存在,频率和持续时间-定义为单词内发声的完全中断。计算敏感性,特异性,阳性和阴性预测值以及似然比的估计值,以确定发声断裂分析的准确性和价值,作为临床诊断测试。结果:1)与MTD相比,ADSD患者的发声中断次数明显增加。 2)所有诊断精度的度量都根据发声中断的持续时间和频率而变化,男性和女性之间的分隔导致不同的诊断测试性能结果。结论:结果表明,发声间隔分析作为将ADSD与MTD区分开的客观测试提供了希望,诊断准确度很高,尤其是在男性中。应该探索声学分析程序的自动化。

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