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首页> 外文期刊>The Laryngoscope: A Medical Journal for Clinical and Research Contributions in Otolaryngology, Head and Neck Medicine and Surgery, Facial Plastic and Reconstructive Surgery .. >Quantitative assessment of laryngeal muscle morphology after recurrent laryngeal nerve injury: right vs. left differences.
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Quantitative assessment of laryngeal muscle morphology after recurrent laryngeal nerve injury: right vs. left differences.

机译:喉返神经损伤后喉肌形态的定量评估:右与左差异。

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摘要

OBJECTIVES/HYPOTHESIS: Reports of laryngeal response to denervation are inconsistent. Some document atrophy and fibrosis in denervated laryngeal muscles, whereas others indicate resistance to atrophy. Spontaneous reinnervation has also been documented. The goal of this study was to clarify the effects of nerve injury and reinnervation on thyroarytenoid (TA) and posterior cricoarytenoid (PCA) muscles. STUDY DESIGN: Laboratory experiment. METHODS: TA and PCA muscles of cats were harvested 5 to 6 months after transecting right or left recurrent laryngeal nerve (RLN). Images of muscle cross-sections were acquired and studied using an image analysis workstation. Cross-sectional areas as well as total cross-sectional area of randomly selected muscle fibers were recorded. RESULTS: TA reinnervation was robust on both sides, but there was less reinnervation of the PCA muscle after left-sided RLN lesion than after right-sided injury. CONCLUSIONS: Differences in reinnervation after RLN injury could contribute to the higher clinical incidence of left- vs. right-sided laryngeal paralysis.
机译:目的/假设:喉部对神经支配反应的报道不一致。一些记录了失神经的喉肌萎缩和纤维化,而另一些则表明对萎缩有抵抗力。自发神经支配也有文献记载。这项研究的目的是阐明神经损伤和神经支配对甲状腺素类固醇(TA)和后环环缝状艾美体(PCA)肌肉的影响。研究设计:实验室实验。方法:横断右或左喉返神经(RLN)后5至6个月,收获猫的TA和PCA肌肉。使用图像分析工作站获取和研究肌肉横截面的图像。记录随机选择的肌肉纤维的横截面面积以及总横截面面积。结果:TA的神经支配在两侧都很牢固,但左侧RLN病变后的PCA肌肉的神经支配要少于右侧损伤后。结论:RLN损伤后神经支配的差异可能导致左侧和右侧喉麻痹的临床发生率较高。

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