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首页> 外文期刊>The American Journal of Cardiology >Computed Tomography-Derived Parameters of Myocardial Morphology and Function in Black and White Patients With Acute Chest Pain
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Computed Tomography-Derived Parameters of Myocardial Morphology and Function in Black and White Patients With Acute Chest Pain

机译：计算机断层摄影术得出的黑白急性胸痛患者的心肌形态和功能参数

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Blacks have higher mortality and hospitalization rates because of congestive heart failure compared with white counterparts. Differences in cardiac structure and function may contribute to the racial disparity in cardiovascular outcomes. Our aim was to compare computed tomography (CT) derived cardiac measurements between black patients with acute chest pain and age- and gender-matched white patients. We performed a retrospective analysis under an institutional review board waiver and in Health Insurance. Portability and Accountability Act compliance. We investigated patients who underwent cardiac dual-source CT for acute chest pain. Myocardial mass, left ventricular (LV) ejection fraction, LV end-systolic volume, and LV end-diastolic volume were quantified using an automated analysis algorithm. Septal wall thickness and cardiac chamber diameters were manually measured. Measurements were compared by independent t test and linear regression. The study population consisted of 300 patients (150 black mean age 54 +/- 12 years; 46% men; 150 white mean. age 55 +/- 11 years; 46% men). Myocardial mass was larger for blacks compared with white (176.1 +/- 58.4 vs 155.9 +/- 51.7 g, p = 0.002), which remained significant after adjusting for age, gender, body mass index, and hypertension. Septal wall thickness was slightly greater (11.9 +/- 2.7 vs 11.2 +/- 3.1 mm, p =.0.036). The LV inner diameter was moderately larger in black patients in systole (32.3 +/- 9.0 vs 30.1 +/- 5.4 ml, p = 0.010) and in diastole (50.1 +/- 7.8 vs 48.9 +/- 5.2 ml, p = 0.137), as well as LV end-diastolic volume (134.5 +/- 42.7 vs 128.2 +/- 30.6 ml, p = 0.143). Ejection fraction was nonsignificantly lower in blacks. (67.1 +/- 13.5% vs 69.0 +/- 9.6%, p = 0.169). In conclusion, CT-derived myocardial mass was larger in blacks compared with whites, whereas LV functional parameters were generally not statistically different, suggesting that LV mass might be a possible contributing factor to the higher rate of cardiac events in blacks. (C) 2016 Elsevier Inc. All rights reserved.
机译：与白人相比，由于充血性心力衰竭，黑人的死亡率和住院率更高。心脏结构和功能的差异可能导致心血管预后方面的种族差异。我们的目的是比较患有急性胸痛的黑人患者与年龄和性别匹配的白人患者之间的计算机断层扫描（CT）心脏测量结果。我们根据机构审查委员会豁免和健康保险进行了回顾性分析。符合《可移植性和责任法案》。我们调查了接受心脏双源CT治疗的急性胸痛患者。使用自动分析算法对心肌质量，左心室射血分数，左室收缩末期容积和左室舒张末期容积进行定量。手动测量间隔壁的厚度和心腔直径。通过独立的t检验和线性回归比较测量结果。研究人群包括300名患者（150名黑人平均年龄54 +/- 12岁; 46％男性; 150名白人平均年龄55 +/- 11岁; 46％男性）。黑人的心肌质量比白人大（176.1 +/- 58.4 vs 155.9 +/- 51.7 g，p = 0.002），在调整了年龄，性别，体重指数和高血压后，黑人的心肌质量仍然显着。隔壁厚度略大（11.9 +/- 2.7对11.2 +/- 3.1毫米，p = .0.036）。黑人患者的收缩期（32.3 +/- 9.0 vs 30.1 +/- 5.4 ml，p = 0.010）和舒张期（50.1 +/- 7.8 vs 48.9 +/- 5.2 ml，p = 0.137）的LV内径适度更大）以及左室舒张末期容积（134.5 +/- 42.7 vs 128.2 +/- 30.6 ml，p = 0.143）。黑人的射血分数显着降低。 （67.1 +/- 13.5％vs 69.0 +/- 9.6％，p = 0.169）。总之，与白人相比，黑人的CT来源的心肌质量更大，而LV功能参数通常在统计学上没有差异，这表明LV质量可能是黑人心脏事件发生率更高的可能因素。 （C）2016 Elsevier Inc.保留所有权利。

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