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首页> 外文期刊>The Laryngoscope: A Medical Journal for Clinical and Research Contributions in Otolaryngology, Head and Neck Medicine and Surgery, Facial Plastic and Reconstructive Surgery .. >Carotid artery resection and reconstruction with expanded polytetrafluoroethylene for head and neck cancer.
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Carotid artery resection and reconstruction with expanded polytetrafluoroethylene for head and neck cancer.

机译：用扩展的聚四氟乙烯进行颈动脉切除和重建以治疗头颈癌。

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OBJECTIVE: There are controversies on management of carotid artery invasion in advanced head and neck cancer. En bloc resection has been considered a curative modality. In this study, we evaluated the feasibility of using expanded polytetrafluoroethylene (ePTFE) in reconstructing the common carotid artery in patients with carotid artery invasion requiring resection. METHOD: A retrospective study including 13 patients managed from 2002 to 2005. All patients underwent en bloc resection of the tumor and internal carotid artery then reconstructed with ePTFE. RESULTS: All patients had en bloc resection of the tumor together with internal carotid artery and reconstruction with ePTFE. Some patients required wound coverage with myocutaneous flaps in eight patients and local flaps in five patients. Intraoperative shunting was used in all patients. Intraoperative heparin infusion and postoperative low dose aspirin were used to prevent thrombosis. One patient developed graft blowout and he was treated with ligation without hemiplegia. One patient had minor stroke. The follow-up period was 18.4 +/- 8.6 months. No patient suffered from neurological deficit or graft occlusion. Disease survival was 61.5% in 1 year and 38.5% in 2 years. Overall survival was 18.3 months. CONCLUSION: En bloc resection and tumor together with carotid artery and ePTFE reconstruction is shown to be a feasible modality in treatment of advanced head and neck cancer with carotid artery invasion.
机译：目的：晚期头颈癌的颈动脉侵袭处理存在争议。整体切除术被认为是一种治疗方法。在这项研究中，我们评估了在需要切除的颈动脉侵犯患者中，使用膨胀聚四氟乙烯（ePTFE）重建颈总动脉的可行性。方法：一项回顾性研究，包括从2002年至2005年接受治疗的13例患者。所有患者均进行了肿瘤和颈内动脉的整体切除，然后用ePTFE重建。结果：所有患者均行肿瘤切除及颈内动脉全切除，并采用ePTFE重建。一些患者需要用8例肌皮瓣和5例局部皮瓣覆盖伤口。所有患者均进行术中分流。术中使用肝素输注和术后低剂量阿司匹林预防血栓形成。一名患者发生了移植物井喷，他接受了结扎治疗而没有偏瘫。一名患者轻度中风。随访时间为18.4 +/- 8.6个月。没有患者遭受神经功能缺损或移植物阻塞。疾病存活率在1年中为61.5％，在2年中为38.5％。总生存期为18.3个月。结论：整体切除和肿瘤联合颈动脉和ePTFE重建术被证明是治疗晚期颈动脉侵犯头颈癌的一种可行方法。

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