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首页> 外文期刊>The American Journal of Cardiology >Impact of Excess Body Weight on Arterial Structure, Function,and Blood Pressure in Firefighters
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Impact of Excess Body Weight on Arterial Structure, Function,and Blood Pressure in Firefighters

机译：体重过多对消防员动脉结构，功能和血压的影响

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摘要

Cardiovascular disease is the leading cause of death among firefighters. The purpose of the present study was to examine the effect of excess body weight on arterial structure and function and blood pressure (BP) in relatively young, apparently healthy, firefighters. The body mass index, brachial BP, carotid BP, aortic BP, radial augmentation index, central pulse wave velocity, forearm blood flow, forearm vasodilatory capacity, carotid arterial compliance, carotid intima-media thickness, and brachial flow-mediated dilation were assessed in 110 firefighters (aged 29.7 +- 8.0 years). The group was divided into equal tertiles according to the body mass index (<25.9, 25.9 to 29.4, and >=29.5 kg/m~2). Group differences in hemodynamics, anthropometrics, microvascular function, and macrovascu-lar structure and function were tested using multivariate analysis of variance. The obese group was older, heavier, and had a larger waist circumference compared to the lean and overweight groups (p <0.05). The overweight group was also older, heavier, and had a larger waist circumference than the lean group (p <0.05). Compared to the lean group, the overweight and obese groups had a greater systolic BP (p <0.05). The obese group also had a significantly greater mean arterial BP and carotid systolic BP than the lean group (p <0.05). The obese group had greater beta stiffness and elastic modulus compared to the lean and overweight groups (p <0.05), but no group differences were found in endothelial function. In conclusion, in a population of relatively young firefighters, an increased body mass index was associated with elevated peripheral BP and arterial stiffness, with no apparent decrements in endothelial function.
机译：心血管疾病是消防员死亡的主要原因。本研究的目的是研究相对较年轻，看似健康的消防员的超重对动脉结构和功能以及血压（BP）的影响。评估了体重指数，肱动脉BP，颈动脉BP，主动脉BP，radial骨增强指数，中央脉搏波速度，前臂血流量，前臂血管舒张能力，颈动脉动脉顺应性，颈动脉内膜中层厚度和肱动脉血流介导的扩张110名消防员（年龄29.7±8.0岁）。根据体重指数（<25.9、25.9至29.4和> = 29.5 kg / m〜2）将其分为相等的三分位数。使用多变量方差分析测试了血液动力学，人体测量学，微血管功能以及大血管结构和功能的组差异。与苗条和超重组相比，肥胖组年龄更大，更重并且腰围更大（p <0.05）。超重组也比瘦组更大，更重并且腰围更大（p <0.05）。与瘦肉组相比，超重和肥胖组的收缩压更高（p <0.05）。肥胖组的平均动脉血压和颈动脉收缩压也明显高于瘦组（p <0.05）。肥胖组比瘦组和超重组具有更高的β刚度和弹性模量（p <0.05），但是在内皮功能方面没有发现组差异。总之，在相对年轻的消防员人群中，体重指数的升高与外周血压和动脉僵硬度的升高有关，而内皮功能没有明显的下降。

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