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首页> 外文期刊>The American Journal of Cardiology >Relation of epicardial fat thickness to right ventricular cavity size in obese subjects.
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Relation of epicardial fat thickness to right ventricular cavity size in obese subjects.

机译:肥胖受试者心外膜脂肪厚度与右心室腔大小的关系。

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摘要

Epicardial fat is the visceral fat depot of the heart and is commonly increased in obese subjects. Obesity is also associated with right ventricular (RV) enlargement. Nevertheless, whether epicardial fat might be independently associated with RV morphology is unknown. I evaluated the correlation between echocardiographic epicardial fat and RV cavity size in subjects with a wide range of adiposity. Echocardiographic epicardial fat thickness and RV end-diastolic diameter (RVEDD) were assessed in 50 obese and 50 normal weight subjects. Patients with clinical conditions that could affect the RVEDD were excluded. Obese subjects had a significantly greater epicardial fat thickness and RVEDD than normal weight subjects (10 +/- 4 vs 5 +/- 2 mm and 22 +/- 10 vs 15 +/- 5, respectively; p <0.01 for both). The univariate relation between the epicardial fat thickness and RVEDD was very significant (r = 0.82, p <0.01) for overall obese and normal weight subjects. Multiple regression analysis showed that epicardial fat thickness was the best independent correlate of RVEDD (r(2) = 0.42, p <0.01) in overall subjects. In conclusion, increased RV epicardial fat accumulation is associated with enlarged RV cavity size.
机译:心外膜脂肪是心脏的内脏脂肪库,在肥胖的受试者中通常会增加。肥胖也与右心室(RV)增大有关。然而,尚不清楚心外膜脂肪是否可能与RV形态独立相关。我评估了范围广泛的肥胖患者的超声心动图心外膜脂肪与右室腔大小之间的相关性。在50例肥胖和50例正常体重的受试者中评估了超声心动图心外膜脂肪厚度和RV舒张末期直径(RVEDD)。排除可能影响RVEDD的临床状况的患者。肥胖受试者的心外膜脂肪厚度和RVEDD明显高于正常体重受试者(分别为10 +/- 4 vs 5 +/- 2 mm和22 +/- 10 vs 15 +/- 5;两者均p <0.01)。对于总体肥胖和正常体重的受试者,心外膜脂肪厚度与RVEDD之间的单变量关系非常显着(r = 0.82,p <0.01)。多元回归分析表明,心外膜脂肪厚度是RVEDD的最佳独立相关性(r(2)= 0.42,p <0.01)。总之,增加的RV心外膜脂肪积聚与RV腔增大有关。

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