...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>The Laryngoscope: A Medical Journal for Clinical and Research Contributions in Otolaryngology, Head and Neck Medicine and Surgery, Facial Plastic and Reconstructive Surgery .. >A systematic analysis of septal deviation associated with rhinosinusitis.
【24h】

A systematic analysis of septal deviation associated with rhinosinusitis.

机译：对鼻-鼻窦炎相关的室间隔偏差的系统分析。

获取原文
获取原文并翻译 | 示例
   

获取外文期刊封面封底 >>

       
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

OBJECTIVES/HYPOTHESIS: Rhinosinusitis might have many etiologies that lead to a common presentation of inflammation and impaired mucociliary clearance. Anatomic factors were once thought to play a large role in the pathogenesis of rhinosinusitis, and septal deviation was examined in multiple studies with conflicting results. With the more recent appreciation that the development of rhinosinusitis is likely multifactorial, it is appropriate to re-examine possible anatomic etiologies. A systematic analysis of septal deviation and rhinosinusitis was therefore performed to better define this association and describe possible etiologic mechanisms. Examination of a large sample, accomplished through systematically identifying and combining previous studies, may compensate for the several shortcomings of these separate analyses. A systematic analysis was therefore performed to answer the question, is septal deviation associated with rhinosinusitis? STUDY DESIGN: Systematic analysis of previously published studies. METHODS: Following a structured literature search, articles examining the association of septal deviation and rhinosinusitis were analyzed quantitatively and qualitatively. Based on the quantitative results, a septal deviation angle (SDA) cutoff of 10 degrees was chosen for distinguishing positive from negative for septal deviation in the qualitative analysis. RESULTS: Of over 300 references initially identified, 13 articles comprised the basis of this review. Increasing angles of septal deviation were associated with increasing prevalence of rhinosinusitis in multiple studies. Combining the results of five previous studies on this subject demonstrated significant association of septal deviation and rhinosinusitis (P = .0004, chi(2) analysis). The clinical effect was found, however, to be modest with an odds ratio of 1.47. Interestingly, in all studies that examined the laterality of rhinosinusitis associated with septal deviation, inflammation was found bilaterally. Based on the data from this analysis, it appears that many of the previous analyses were insufficiently powered to detect an association between rhinosinusitis and septal deviation. Others failed to find an association by examining subjects with small SDAs. CONCLUSIONS: Septal deviation is associated with an increased prevalence of rhinosinusitis, although the impact of this anatomic anomaly is limited. It appears to be one of many possible factors that might lead to the development of rhinosinusitis.
机译：目的/假设：鼻-鼻窦炎可能有多种病因，导致常见的炎症反应和粘膜纤毛清除功能受损。曾经有人认为解剖因素在鼻-鼻窦炎的发病机制中起着重要作用，并且在多项研究中检查了间隔偏差，结果相互矛盾。随着最近对鼻-鼻窦炎的发展可能是多因素的认识，重新检查可能的解剖病因是适当的。因此，对室间隔偏斜和鼻-鼻窦炎进行了系统分析，以更好地定义这种关联并描述可能的病因机制。通过系统地识别和合并以前的研究来完成的大样本检查，可以弥补这些单独分析的一些不足。因此进行了系统的分析来回答这个问题，鼻中隔是否与鼻窦炎相关？研究设计：对先前发表的研究的系统分析。方法：在进行结构化文献检索后，对定性与鼻中隔偏差相关的文章进行了定量和定性分析。根据定量结果，在定性分析中选择10度的隔片偏离角（SDA）截止值以区分隔片偏离的正负。结果：在最初确定的300多个参考文献中，有13篇文章构成了此次审查的基础。在多项研究中，鼻中隔偏角的增加与鼻-鼻窦炎的患病率增加相关。结合先前关于该主题的五项研究的结果，显示出室间隔偏差和鼻-鼻窦炎之间存在显着关联（P = .0004，chi（2）分析）。然而，发现临床效果中等，比值比为1.47。有趣的是，在所有检查与鼻中隔偏斜相关的鼻－鼻窦炎的研究中，发现双侧发炎。根据来自此分析的数据，似乎许多先前的分析不足以检测鼻-鼻窦炎和间隔偏斜之间的关联。其他人则没有通过检查具有小的SDA的受试者来找到关联。结论：鼻中隔偏曲与鼻-鼻窦炎的患病率增加有关，尽管这种解剖异常的影响是有限的。它似乎是可能导致鼻-鼻窦炎发展的许多可能因素之一。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号