...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>The American Journal of Cardiology >Safety and Efficacy of Staged Percutaneous Coronary Intervention During Index Admission for ST-Elevation Myocardial Infarction With Multivessel Coronary Disease (Insights from the University of Ottawa Heart Institute STEMI Registry)
【24h】

Safety and Efficacy of Staged Percutaneous Coronary Intervention During Index Admission for ST-Elevation Myocardial Infarction With Multivessel Coronary Disease (Insights from the University of Ottawa Heart Institute STEMI Registry)

机译：ST抬高型心肌梗死合并多支冠状动脉疾病的指数准入期间分阶段经皮冠状动脉介入治疗的安全性和有效性（渥太华大学心脏研究所STEMI注册表提供的见解）

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The optimal management strategy for patients with ST-elevation myocardial infarction (STEMI) and multivessel disease has not been well established. In the present cohort study, we sought to examine the safety and efficacy of inhospital staged PCI for patients with STEMI and multivessel disease. We identified all patients with STEMI referred for primary PCI who were found to have multivessel disease (stenosis >= 50% in nonculprit vessel) and compared clinical outcomes in relation to the management strategy, staged versus culprit-only PCI, for nonculprit vessel disease. The primary outcome was mortality at 180 days, and secondary outcomes included mortality during the index hospitalization and at 30 days, myocardial infarction, stent thrombosis, stroke, and bleeding. Of the 1,038 patients with STEMI meeting inclusion criteria, 259 (25%) underwent staged PCI and 779 (75%) culprit-only PCI during the index admission. Mortality at 180 days was 0.8% in patients with staged PCI and 5.0% in patients with culprit-only PCI (p = 0.003). The association between staged PCI and reduced mortality persisted after adjusting for baseline differences in patient characteristics and angiographic variables between the 2 cohorts (odds ratio 0.2, 95% confidence interval 0.04 to 0.77, p = 0.02). The rates of inhospital reinfarction in the staged and culprit-only PCI cohorts were 0.8% versus 1.3% (p = 0.50), respectively, stent thrombosis 0.8% versus 1.3% (p = 0.50), and stroke 0.4% versus 1.3% (p = 0.31). There were no inhospital adverse events related to acute occlusion of a nonculprit vessel in either cohort. Staged PCI during index admission is a safe and effective revascularization strategy for patients with STEMI and multivessel disease. (C) 2015 Elsevier Inc. All rights reserved.
机译：ST抬高型心肌梗死（STEMI）和多支血管疾病的最佳治疗策略尚未确立。在本队列研究中，我们试图检查住院分期PCI对STEMI和多支血管疾病患者的安全性和有效性。我们确定了所有被诊断为原发性PCI的STEMI患者，发现他们患有多支血管疾病（非罪犯血管中狭窄> = 50％），并比较了非罪犯血管疾病与分期冠心病PCI治疗的临床疗效和分期管理。主要结局为180天死亡率，次要结局包括指数住院和30天时的死亡率，心肌梗塞，支架血栓形成，中风和出血。在1,038例符合入选标准的STEMI患者中，有259例（25％）接受了分期PCI治疗，而779例（75％）仅采用罪犯PCI治疗。分期行PCI的患者180天死亡率为0.8％，而单纯行PCI的患者为5.0％（p = 0.003）。在调整两组患者之间的基线特征和血管造影变量之间的基线差异后，分期PCI与死亡率降低之间的关联仍然存在（优势比为0.2，95％置信区间为0.04至0.77，p = 0.02）。在分阶段和仅罪犯的PCI队列中，院内再梗死发生率分别为0.8％和1.3％（p = 0.50），支架内血栓形成为0.8％和1.3％（p = 0.50），中风为0.4％和1.3％（p = 0.31）。在任何一个队列中，均没有与非罪犯血管的急性阻塞相关的院内不良事件。对于患有STEMI和多支血管疾病的患者，指数入院期间分期PCI是一种安全有效的血运重建策略。 （C）2015 Elsevier Inc.保留所有权利。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号