...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>The American Journal of Cardiology >Vascular Complications and Bleeding After Transfemoral Transcatheter Aortic Valve Implantation Performed Through Open Surgical Access
【24h】

Vascular Complications and Bleeding After Transfemoral Transcatheter Aortic Valve Implantation Performed Through Open Surgical Access

机译：通过开放式外科手术入路经股动脉经导管主动脉瓣植入后的血管并发症和出血

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Major vascular, complications (VC) remain frequent after transcatheter aortic valve implantation (TAVI) and may be associated with unfavorable clinical outcomes. The objective of this study was to evaluate the rate of VC after transfemoral TAVI performed using an exclusive open surgical access strategy. From 2010 to 2014, we included in a monocentric registry all consecutive patients who underwent transfemoral TAVI. The procedures were performed with 16Fr to 20Fr sheath systems. VC were evaluated within 30 days and classified as major or minor according to the Valve Academic Research Consortium 2 definition. The study included 396 patients, 218 were women (55%), median age was 85 years (81 to 88), and the median logistic Euroscore was 15.2% (11 to 23). The balloon-expandable SAPIEN XT and the self-expandable Medtronic Core Valve prosthesis were used in 288 (72.7%) and 108 patients (27.3%), respectively. The total length of the procedure was 68 +/- 15 minutes including 13 +/- 5 minutes for the open surgical access. Major and minor VC were observed in 9 (2.3%) and 16 patients (4%), respectively, whereas life-threatening and major bleeding concerned 18 patients (4.6%). The median duration of hospitalization was 5 days (interquartile range 2 to 7), significantly higher in patients with VC (7 days [5 to 15], p < 0.001). Mortality at 1-month and 1-year follow-up (n = 26, 6.6%; and n = 67, 17.2%, respectively) was not related to major or minor VC (p = 0.6). In multivariable analysis, only diabetes (odds ratio 2.5, 95% confidence interval 1.1 to 6.1, p = 0.034) and chronic kidney failure (odds ratio 3.0, 95% confidence interval 1.0 to 9.0, p = 0.046) were predictive of VC, whereas body mass index, gender, Euroscore, and lower limb arteriopathy were not. In conclusion, minimal rate of VC and bleeding can be obtained after transfemoral TAVI performed using an exclusive surgical strategy, with a particular advantage observed in high-risk bleeding patients. (C) 2015 Elsevier Inc. All rights reserved.
机译：经导管主动脉瓣植入术（TAVI）后，主要血管并发症（VC）仍然很常见，并且可能与不良的临床结果相关。这项研究的目的是评估使用独家开放式外科手术策略经股骨TAVI术后的VC率。从2010年到2014年，我们将所有经股TAVI的连续患者纳入单中心登记。该程序在16Fr至20Fr护套系统中进行。在30天内评估了VC，并根据Valve Academic Research Consortium 2的定义将其分为主要或次要类别。该研究包括396位患者，其中218位为女性（55％），中位年龄为85岁（81至88岁），后勤Euroscore中位值为15.2％（11至23岁）。球囊扩张式SAPIEN XT和自扩张式Medtronic核心瓣膜假体分别用于288例（72.7％）和108例患者（27.3％）。该过程的总长度为68 +/- 15分钟，包括开放式手术通道的13 +/- 5分钟。分别有9名患者（2.3％）和16名患者（4％）观察到了主要和次要VC，而威胁生命和主要出血的18位患者（4.6％）。中位住院时间为5天（四分位数范围为2至7），而VC患者的中位数为7天[5至15]，p <0.001）。 1个月和1年随访时的死亡率（分别为n = 26，6.6％; n = 67，17.2％）与主要或次要的VC无关（p = 0.6）。在多变量分析中，只有糖尿病（几率2.5，95％置信区间1.1至6.1，p = 0.034）和慢性肾衰竭（几率3.0，95％置信区间1.0至9.0，p = 0.046）可预测VC，而体重指数，性别，Euroscore和下肢动脉病变没有。综上所述，使用独家手术策略经股骨TAVI手术后，可以获得最低的VC和出血率，在高危出血患者中观察到特别的优势。 （C）2015 Elsevier Inc.保留所有权利。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号