...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>The American Journal of Cardiology >Impact of sleep-disordered breathing on life-threatening ventricular arrhythmia in heart failure patients with implantable cardioverter-defibrillator.
【24h】

Impact of sleep-disordered breathing on life-threatening ventricular arrhythmia in heart failure patients with implantable cardioverter-defibrillator.

机译：睡眠呼吸障碍对植入式心脏复律除颤器心力衰竭患者危及生命的室性心律失常的影响。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

It was recognized that sleep-disordered breathing (SDB) is associated with cardiac arrhythmia and sudden cardiac death. However, it was unclear whether the presence of SDB increased the risk of life-threatening ventricular arrhythmia in patients with heart failure (HF) with an implantable cardioverter-defibrillator (ICD). Seventy-one patients with HF and an ICD who were followed up for 180 days after a sleep study were prospectively studied. All patients had an ejection fraction or=10 events/hour on the sleep study. The frequency of appropriate ICD therapy and the day-night pattern of ICD therapies were compared between patients with and without SDB. SDB was diagnosed in 47 of 71 patients (66%). There were no statistical differences between patients with and without SDB in baseline cardiac function. However, appropriate ICD therapies occurred more frequently in patients with (43%) than without SDB (17%; p = 0.029). On multivariate analysis, the presence of SDB was an independent predictor for appropriate ICD therapy (hazard ratio 4.05, 95% confidence interval 1.20 to 13.65, p = 0.015). Moreover, the rate of total ICD therapy from midnight to 6 A.M. was significantly higher in patients with (34%) than without SDB (13%; p = 0.046). In conclusion, in patients with HF with an ICD, the presence of SDB was common and an independent predictor of life-threatening ventricular arrhythmias that were more likely to occur during sleep.
机译：人们认识到睡眠呼吸障碍（SDB）与心律不齐和心源性猝死有关。然而，尚不清楚SDB的存在是否会增加使用植入式心脏复律除颤器（ICD）的心力衰竭（HF）患者危及生命的室性心律失常的风险。前瞻性研究了睡眠研究后随访180天的71例HF和ICD患者。所有患者的射血分数<或= 35％。在睡眠研究中，SDB被定义为呼吸暂停低通气指数≥10事件/小时。比较有无SDB患者的适当ICD治疗频率和ICD治疗的白天模式。 71名患者中有47名（66％）被诊断为SDB。有和没有SDB的患者之间在基线心功能方面无统计学差异。但是，有适当ICD治疗的患者（43％）比没有SDB的患者（17％; p = 0.029）更频繁。在多变量分析中，SDB的存在是适当ICD治疗的独立预测因素（危险比4.05，95％置信区间1.20至13.65，p = 0.015）。此外，从午夜到凌晨6点的总ICD治疗率。有SDB的患者（34％）明显高于无SDB的患者（13％; p = 0.046）。总之，在患有ICD的HF患者中，SDB的存在很普遍，并且是威胁生命的室性心律失常的独立预测因子，这种可能性在睡眠期间更容易发生。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号