BOVINE PAPILLOMAVIRUS AND CANCER [Review]

Campo MS.

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BOVINE PAPILLOMAVIRUS AND CANCER [Review]

机译：牛乳头状瘤病毒和癌症[评论]

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Bovine papillomavirus (BPV) induces papillomas of cutaneous or mucosal epithelia in cattle. The papillomas are benign tumours and generally regress, but occasionally persist and provide the focus for malignant transformation to squamous cell carcinoma, particularly in the presence of environmental cofactors. This has been experimentally demonstrated for BPV-2 and cancer of the urinary bladder, and BPV-4 and cancer of the upper alimentary canal in cattle feeding on bracken fern. In this review, several aspects of the biology of the virus are described including viral genome structure, regulation of transcription of the viral oncogenes, function of the viral oncoproteins, cooperation between virus and chemical cofactors in carcinogenesis, virus latency and prophylactic and therapeutic vaccination programmes.

机译：牛乳头瘤病毒（BPV）诱导牛的皮肤或粘膜上皮乳头状瘤。乳头状瘤是良性肿瘤，通常会消退，但偶尔会持续存在，并为恶性转化为鳞状细胞癌提供了重点，尤其是在环境辅助因子存在的情况下。实验证明了以蕨菜为食的牛的BPV-2和膀胱癌，BPV-4和上消化道癌症。在这篇综述中，描述了病毒生物学的几个方面，包括病毒基因组结构，病毒癌基因转录的调控，病毒癌蛋白的功能，病毒和化学辅因子在致癌，病毒潜伏期以及预防性和治疗性疫苗接种计划方面的合作。。

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来源
《The Veterinary Journal》 |1997年第3期|共14页
作者
Campo MS.;
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正文语种 eng
中图分类动物医学（兽医学）;
关键词
Papillomavirus; Cancer; Cell transformation; Cofactors; Vaccination.; Long control region; Cottontail rabbit papillomavirus; Hpv18 regulatory; region; Open reading frame; Viral e2 protein; E5 oncoprotein.; Gene product; Type 16 e7; Mucosal papillomavirus; Cell transformation;

机译：乳头瘤病毒;癌;细胞转化;辅因子;疫苗接种;长控制区;牛尾兔乳头瘤病毒;Hpv18调控;区域;开放阅读框;病毒e2蛋白;E5癌蛋白;基因产物;16 e7型;粘膜乳头瘤病毒;细胞转化;

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专利

1. BOVINE PAPILLOMAVIRUS AND CANCER [Review] [J] . Campo MS. The Veterinary Journal . 1997,第3期

机译：牛乳头状瘤病毒和癌症[评论]
2. Bovine papillomavirus prostate cancer antigen virus-like particle vaccines are efficacious in advanced cancers in the TRAMP mouse spontaneous prostate cancer model [J] . Simons Brian W., Cannella Fabiana, Rowley Dayana T., Cancer immunology, immunotherapy : . 2020,第4期

机译：牛乳头瘤病毒前列腺癌抗原病毒样颗粒疫苗在流动鼠枪自发前列腺癌模型中是有效的癌症
3. Are Health Care Professionals Prepared to Implement Human Papillomavirus Testing? A Review of Psychosocial Determinants of Human Papillomavirus Test Acceptability in Primary Cervical Cancer Screening [J] . Journal of women’s health . 2020,第3期

机译：医疗保健专业人士是否准备实施人乳头瘤病毒检测？原发性宫颈癌筛查人乳头瘤病毒试验可接受性的心理社会决定因素综述
4. The IARC Commitment to Cancer Prevention:The Example of Papillomavirus and Cervical Cancer [C] . Silvia Francesch International Society of Cancer Chemoprevention . 2005

机译：IARC对癌症预防的承诺：乳头瘤病毒和宫颈癌的举例
5. Investigations of equine sarcoids and Bovine Papillomavirus in Western Canada. [D] . Wobeser, Bruce K. 2010

机译：加拿大西部马肉结节病和牛乳头瘤病毒的调查。
6. The presence of bovine papillomavirus type 4 DNA is not required for the progression to or the maintenance of the malignant state in cancers of the alimentary canal in cattle. [O] . M S Campo, M H Moar, M L Sartirana, 1985

机译：牛的消化道癌症发展为或维持其恶性状态并不需要牛乳头瘤病毒4型DNA的存在。
7. The interplay of HIV and human papillomavirus-related cancers in sub-Saharan Africa: scoping review [O] . Kabelo Matjie Bridget Lekoane, Desmond Kuupiel, Tivani P. Mashamba-Thompson, 2020

机译：艾滋病毒和人乳头瘤病毒相关癌症在撒哈拉以南非洲的相互作用：裁判审查

BOVINE PAPILLOMAVIRUS AND CANCER [Review]

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