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首页> 外文期刊>Thorax: The Journal of the British Thoracic Society >Respiratory symptoms in older people and their association with mortality.
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Respiratory symptoms in older people and their association with mortality.

机译:老年人的呼吸道症状及其与死亡率的关系。

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BACKGROUND: A study was undertaken to assess the prevalence of reported respiratory symptoms in a population aged over 75 years and their association with mortality. METHODS: A total of 14 458 people aged 75 years and over participating in a trial of health screening of older people in general practice answered questions on three respiratory symptoms: cough, sputum production, and wheeze. The association of symptoms with mortality was examined for all cause and respiratory causes of death taking account of potential confounders. RESULTS: Coughing up phlegm in winter mornings had a prevalence of 27.0% (95% confidence interval (CI) 26.8 to 27.2). Those with this symptom had an adjusted hazard ratio for all cause mortality of 1.35 (95% CI 1.21 to 1.50), p<0.001 and for respiratory specific mortality of 2.01 (95% CI 1.66 to 2.41), p<0.001. Phlegm at any time of the day in winter had a prevalence of 16.5% (95% CI 16.3 to 16.7) with hazard ratios for all cause and respiratory specific mortality of 1.28 (95% CI 1.15 to 1.42) and 2.28 (95% CI 1.92 to 2.70), p<0.001. Wheeze or whistling from the chest had a prevalence of 14.3% (95% CI 14.1 to 14.5) with hazard ratios of 1.45 (95% CI 1.31 to 1.61) and 2.86 (95% CI 2.45 to 3.35), p<0.001. CONCLUSIONS: The prevalence of respiratory symptoms is widespread among elderly people and their presence is a strong predictor of mortality.
机译:背景:进行了一项研究,以评估在75岁以上的人群中报告的呼吸道症状的患病率及其与死亡率的关系。方法:共有14 458名年龄在75岁及以上的人参加了针对老年人的健康筛查试验,该试验回答了有关三种呼吸道症状的问题:咳嗽,痰液产生和喘鸣。考虑了潜在的混杂因素,检查了所有死亡原因和呼吸原因的症状与死亡率之间的关系。结果:冬季早晨咳嗽痰的患病率为27.0%(95%置信区间(CI)为26.8至27.2)。患有此症状的患者的所有病因死亡率的校正风险比为1.35(95%CI 1.61至1.50),p <0.001,呼吸道特异性死亡率为2.01(95%CI 1.66至2.41),p <0.001。冬季每天的任何时间痰液的患病率为16.5%(95%CI 16.3至16.7),所有原因的致病率和呼吸道特定死亡率分别为1.28(95%CI 1.15至1.42)和2.28(95%CI 1.92)至2.70),p <0.001。胸鸣或吹口哨的患病率为14.3%(95%CI为14.1至14.5),危险比为1.45(95%CI为1.31至1.61)和2.86(95%CI为2.45至3.35),p <0.001。结论:呼吸系统症状的流行在老年人中很普遍,他们的存在是死亡率的有力预测指标。

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