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What's wrong with fear conditioning?

机译:恐惧调节有什么问题?

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Fear conditioning is one of the prime paradigms of behavioural neuroscience and a source of tremendous insight in the fundamentals of learning and memory and the psychology and neurobiology of emotion. It is also widely regarded as a model for the pathogenesis of anxiety disorders in a diathesis-stress model of psychopathology. Starting from the apparent paradox between the adaptive nature of fear conditioning and the dysfunctional nature of pathological anxiety, we present a critique of the human fear conditioning paradigm as an experimental model for psychopathology. We discuss the potential benefits of expanding the human fear conditioning paradigm by (1) including action tendencies as an important index of fear and (2) paying more attention to "weak" (i.e., ambiguous) rather than "strong" fear learning situations (Lissek et al., 2006), such as contained in selective learning procedures. We present preliminary data that illustrate these ideas and discuss the importance of response systems divergence in understanding individual differences in vulnerability for the development of pathological anxiety. (C) 2011 Elsevier B.V. All rights reserved.
机译:恐惧调节是行为神经科学的主要范例之一,也是学习和记忆基础以及情绪心理学和神经生物学方面的深刻见解的来源。在心理病理的素质-应激模型中,它也被广泛认为是焦虑症发病机理的模型。从恐惧调节的适应性和病理性焦虑的机能失调之间的明显矛盾出发,我们提出了对人类恐惧调节范式作为心理病理学实验模型的批评。我们讨论了通过以下方式扩展人类恐惧条件范式的潜在好处:(1)将行动倾向作为恐惧的重要指标;(2)更加注意“弱”(即模棱两可)而不是“强”恐惧学习情况( Lissek et al。,2006),例如包含在选择性学习程序中。我们提供了初步的数据,说明了这些想法,并讨论了反应系统差异在理解个体易受病理性焦虑发展的脆弱性方面的重要性。 (C)2011 Elsevier B.V.保留所有权利。

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