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首页> 外文期刊>Transactions of the Royal Society of Tropical Medicine and Hygiene >Correlation of retinal haemorrhages with brain haemorrhages in children dying of cerebral malaria in Malawi.
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Correlation of retinal haemorrhages with brain haemorrhages in children dying of cerebral malaria in Malawi.

机译:马拉维因脑疟疾死亡的儿童的视网膜出血与脑出血的相关性。

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摘要

Retinal haemorrhages increase in number with severity of Plasmodium falciparum malaria and occur in 35-40% of children with cerebral malaria. We performed clinical retinal examinations and histopathological examinations of retina, and parietal and cerebellar sections of the brains, in 33 children in Malawi who died with cerebral malaria, severe malaria anaemia, or coma of other causes. Haemorrhages were counted in a standardized fashion: the Spearman correlation coefficient between the number of haemorrhages in retina and brain was 0.741 for parietal tissue and 0.703 for cerebellar (P < 0.01 for both). Severity of haemorrhage in the retina correlates well with that in the brain. Retinal examination in cerebral malaria is a useful tool in predicting some of the pathophysiological processes occurring in the brain.
机译:视网膜出血的数量随恶性疟原虫疟疾的严重程度而增加,并且在35-40%的脑疟疾患儿中发生。我们在马拉维的33名因脑疟疾,严重疟疾贫血或其他原因昏迷而死亡的儿童中进行了视网膜的临床视网膜检查以及视网膜,大脑顶叶和小脑切片的组织病理学检查。出血以标准化方式进行计数:顶叶组织的视网膜和脑部出血数目之间的Spearman相关系数是0.741(小脑组织)和0.703(小脑)(两者均P <0.01)。视网膜出血的严重程度与大脑出血的严重程度相关。视网膜疟疾的视网膜检查是预测大脑中某些病理生理过程的有用工具。

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