Neurovirulence of four encephalitogenic dengue 3 virus strains isolated in Malaysia (1992-1994) is not attributed to their envelope protein.

Fong MY; Yusup R; Yusof R; Lam SK

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Neurovirulence of four encephalitogenic dengue 3 virus strains isolated in Malaysia (1992-1994) is not attributed to their envelope protein.

机译：在马来西亚（1992-1994年）分离出的四种脑致病性登革热3病毒株的神经毒性不归因于它们的包膜蛋白。

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The amino acid sequences of the envelope (E) protein of four encephalitogenic and five non-encephalitogenic dengue 3 virus strains isolated in Malaysia were determined and compared. Multiple sequence alignment revealed a high degree of similarity in the E protein of the strains suggesting that neurovirulence of these four encephalitogenic strains is not attributed to this protein.

机译：确定并比较了在马来西亚分离的4例致脑炎和5例非致脑炎的登革热3病毒株的包膜（E）蛋白的氨基酸序列。多序列比对揭示了菌株E蛋白中的高度相似性，表明这四种致脑原性菌株的神经毒性不归因于该蛋白。

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《Transactions of the Royal Society of Tropical Medicine and Hygiene》 |2004年第6期|共3页
作者
Fong MY; Yusup R; Yusof R; Lam SK;
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正文语种 eng
中图分类预防医学、卫生学;
关键词
Dengue; Dengue Virus; Encephalitis; Viral; Viral Envelope Proteins; 登革热; 登革热病毒; 脑炎; 病毒性; 病毒包膜蛋白质类;

机译：Dengue;Dengue Virus;Encephalitis;Viral;Viral Envelope Proteins;登革热;登革热病毒;脑炎;病毒性;病毒包膜蛋白质类;

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1. Neurovirulence of four encephalitogenic dengue 3 virus strains isolated in Malaysia (1992-1994) is not attributed to their envelope protein. [J] . Fong MY, Yusup R, Yusof R, Transactions of the Royal Society of Tropical Medicine and Hygiene . 2004,第6期

机译：在马来西亚（1992-1994年）分离出的四种脑致病性登革热3病毒株的神经毒性不归因于它们的包膜蛋白。
2. The neurovirulence and neuroinvasiveness of chimeric tick-borne encephalitis/dengue virus can be attenuated by introducing defined mutations into the envelope and NS5 protein genes and the 3' non-coding region of the genome. [J] . Engel AR, Rumyantsev AA, Maximova OA, Virology . 2010,第1期

机译：嵌合tick传脑炎/登革热病毒的神经毒性和神经侵袭性可以通过将定义的突变引入包膜和NS5蛋白基因以及基因组的3'非编码区来减弱。
3. Dengue Virus Envelope Dimer Epitope Monoclonal Antibodies Isolated from Dengue Patients Are Protective against Zika Virus [J] . J. A. Swanstrom, J. A. Plante, K. S. Plante, MBio . 2016,第4期

机译：从登革热患者中分离出的登革热病毒包膜二聚体表位单克隆抗体对寨卡病毒具有保护作用
4. Identification of natural products as an inhibitor of β-OG pocket binder of dengue virus envelope protein using fragment-based drug design and molecular docking approach [C] . U. S. F. Tambunan, A. H. Alkaff International Symposium on Current Progress in Mathematics and Sciences . 2018

机译：用基于片段的药物设计和分子对接方法鉴定天然产物作为登革热病毒包膜蛋白β-OG口袋粘合剂的抑制剂
5. Mutagenesis of the dengue virus envelope glycoprotein gene can significanltly alter virus infectivity phenotypes in cultured cells and live mosquitoes. [D] . Erb, Steven Michael. 2011

机译：登革热病毒包膜糖蛋白基因的诱变可以显着改变培养细胞和活蚊子中的病毒感染性表型。
6. Nucleotide sequence of the envelope protein gene of a Malaysian dengue-2 virus isolated from a patient with dengue haemorrhagic fever. [O] . S Samuel, C L Koh, J Blok, 1989

机译：从登革出血热患者中分离出的马来西亚登革2病毒包膜蛋白基因的核苷酸序列。
7. Nucleotide sequence of the envelope protein gene of a Malaysian dengue-2 virus isolated from a patient with dengue haemorrhagic fever. [O] . Samuel, S, Koh, C L, Blok, J, 1989

机译：从登革出血热患者中分离出的马来西亚登革2病毒包膜蛋白基因的核苷酸序列。
8. Development of Safe, Effective Vaccines for Dengue Virus Disease by RecombinantBaculovirus. Subtitle: Development of Safe, Effective Vaccines for Dengue Disease Utilizing Viral Envelope and NSI Glycoproteins Expressed by Recombinant Baculovirus [R] . Lai, C. J. 1991

机译：利用重组杆状病毒开发安全有效的登革病毒疫苗。副标题：利用重组杆状病毒表达的病毒包膜和NsI糖蛋白开发安全有效的登革病疫苗

Neurovirulence of four encephalitogenic dengue 3 virus strains isolated in Malaysia (1992-1994) is not attributed to their envelope protein.

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