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The association of living conditions and lifestyle factors with burden of cysts among neurocysticercosis patients in Ecuador

机译:厄瓜多尔神经囊尾osis病患者的生活状况和生活方式因素与囊肿负担的关系

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摘要

We used baseline data on 154 symptomatic neurocysticercosis (NCC) patients in Ecuador to identify predictors of the burden of cysts. We ran logistic regression models with the burden of cysts as the outcome, defined as the number of cysts in the brain (1 vs >1), and having cysts in all 3 phases of evolution (active, transitional and calcifications) vs <3. These two outcomes are thought to be indicators of exposure dose and/or repeated exposure over time. The predictors examined were: living in a rural area, living on a dirt road, living in an adobe or wood house (vs brick/cement), no running water in the house, no bathroom in the house, having a domestic employee cook in the home, eating most meals at restaurants or street vendors, working in a manual labour job.We found that the odds of having multiple NCC cysts was higher among those working in manual labour (OR=3.5, p=0.004), and those who ate most meals outside the home had higher odds of having cysts in all 3 phases (OR=5.0, p=0.007). Burden of cysts may be a useful outcome when looking to identify exposure risk factors in the absence of an uninfected control group.
机译:我们使用了154例厄瓜多尔症状性神经囊虫病(NCC)患者的基线数据来确定囊肿负担的预测因子。我们运行了逻辑回归模型,将囊肿的负担作为结果,定义为大脑中囊肿的数量(1比> 1),并且在进化的所有3个阶段(活动,过渡和钙化)囊肿均小于<3。这两个结果被认为是暴露剂量和/或随时间重复暴露的指标。所检查的预测因素是:住在农村地区,住在土路上,住在土坯房或木屋(相对于砖/水泥),房屋中没有自来水,房屋中没有浴室,有家庭雇工做饭我们发现,在从事体力劳动的人(OR = 3.5,p = 0.004)和那些从事体力劳动的人中,患有多个NCC囊肿的几率更高。在家外用餐的大多数人在所有三个阶段中都有囊肿的可能性更高(OR = 5.0,p = 0.007)。当试图在没有未感染对照组的情况下确定暴露危险因素时,囊肿负担可能是有用的结果。

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