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首页> 外文期刊>Transactions of the Royal Society of Tropical Medicine and Hygiene >Enteric pathogens in HIV infected and HIV uninfected individuals with diarrhea in Pune
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Enteric pathogens in HIV infected and HIV uninfected individuals with diarrhea in Pune

机译：浦那感染艾滋病毒和未感染艾滋病毒的腹泻患者中的肠道病原体

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Background: Diarrhea in HIV infected individuals is acommoncomplication seen in about90%of patients in developing countries. The objective of this study was to identify enteric pathogens in HIV infected and HIV uninfected individuals in Pune. Method: This study was conducted from January 2009 to May 2010 on 331 consecutive patients presenting with diarrhea admitted at Naidu Municipal Corporation Hospital, Pune and processed using conventional methods. Results: Intestinal parasitic pathogens were detected in 60% (39/65) of HIV infected and 14.3 (38/266) of HIV uninfected individuals. Bacterial pathogens were detected in 34% (22/65) of HIV infected individuals and 28.2% (75/266) of the HIV uninfected individuals. The common enteric pathogens detected in HIV infected individuals were Cystoisospora belli (28%, 18/65) followed by Cryprotosporidium parvum (12%, 8/65). In HIV uninfected individuals Entamoeba histolytica (7.1%, 19/266) followed by Shigella flexnari (4.9%, 13/266) were the most commonpathogens. The difference in detection of enteric parasites in HIV infected individuals and HIVuninfected individuals was found to be significant (p,0.01). Conclusions: Intestinal parasitic pathogens aremorecommonin HIV infectedantiretroviral therapyna?ve patients. Early detection of enteric pathogens by routine examination of stool samples will help in the management and to improve the quality of life for HIV infected individuals.
机译：背景：在发展中国家，约有90％的患者出现了HIV感染者腹泻的并发症。这项研究的目的是在浦那确定HIV感染者和HIV未感染者的肠道病原体。方法：该研究于2009年1月至2010年5月在浦那奈杜市公立医院收治的331例出现腹泻的连续患者中进行，并采用常规方法进行处理。结果：在60％（39/65）的HIV感染者和14.3（38/266）的HIV未感染者中检出了肠道寄生虫病原体。在34％（22/65）的HIV感染者和28.2％（75/266）的HIV未感染者中发现了细菌病原体。在HIV感染者中检测到的常见肠道病原体是Bellyisoisospora belli（28％，18/65），其次是Cryprotosporidium parvum（12％，8/65）。在未感染艾滋病毒的个体中，溶组织变形杆菌（7.1％，19/266），其次是弗氏志贺氏菌（4.9％，13/266），是最常见的病原体。发现在感染HIV的个体和未感染HIV的个体中肠道寄生虫的检测差异显着（p，0.01）。结论：肠道寄生虫病原体为HIV感染的抗逆转录病毒疗法。通过常规检查粪便样本来及早发现肠道病原体，将有助于管理和改善HIV感染者的生活质量。

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