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首页> 外文期刊>Transactions of the American Ophthalmological Society. >Acute hydrops in the corneal ectasias: associated factors and outcomes.
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Acute hydrops in the corneal ectasias: associated factors and outcomes.

机译：角膜扩张的急性积液：相关因素和预后。

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摘要

PURPOSE: To identify factors associated with the development of hydrops and affecting its clinical outcome. METHODS: Chart review of all patients with acute hydrops seen by a referral cornea service during a 2.5-year period between June 1996 and December 1998. RESULTS: Twenty-one patients (22 eyes) with acute hydrops were seen. Nineteen patients had keratoconus, 2 had pellucid marginal degeneration, and 1 had keratoglobus. Twenty-one of 22 (95%) eyes had seasonal allergies and 20 of 22 (91%) eyes had allergy-associated eye-rubbing behavior. Six of 22 (27%) had a diagnosis of Down's syndrome. Six patients were able to identify a traumatic inciting event: vigorous eye rubbing in 4 and traumatic contact lens insertion in 2. The affected area ranged from 7% to 100% of the corneal surface area and was related to disease duration and final visual acuity. Proximity of the area of edema to the corneal limbus ranged from 0 to 2.3 mm and was also related to prognosis. Three serious complications were observed: a leak, an infectious keratitis, and an infectious keratitis and coincidental neovascular glaucoma. Various medical therapies did not differ significantly in their effect on outcome, and ultimately 4 (18%) of 22 patients underwent penetrating keratoplasty. Best-corrected visual acuity was equal to or better than prehydrops visual acuity in 5 of the 6 patients in whom prehydrops visual acuity was known, without corneal transplantation. CONCLUSIONS: Allergy and eye-rubbing appear to be important risk factors in the development of hydrops. Visual results are acceptable in some patients without surgery. Close observation allows for the early detection and treatment of complications such as perforation and infection.
机译：目的：确定与积水发展有关并影响其临床结局的因素。方法：在1996年6月至1998年12月的2.5年期间，通过转诊角膜服务看到的所有急性积液患者的图表回顾。结果：观察到21例急性积液患者（22眼）。圆锥角膜19例，边缘透明变性2例，圆锥角膜1例。 22只（21％）眼睛中有21只具有季节性过敏，22只（91％）眼睛中有20只具有与过敏相关的揉眼行为。 22人中有6人（占27％）被诊断出唐氏综合症。六名患者能够识别出创伤性煽动事件：剧烈摩擦眼睛4次，插入角膜接触镜2次。患病面积为角膜表面积的7％至100％，与疾病持续时间和最终视力有关。水肿区域与角膜缘的接近范围为0到2.3 mm，也与预后有关。观察到三个严重的并发症：渗漏，感染性角膜炎，感染性角膜炎和巧合的新生血管性青光眼。各种药物疗法对预后的影响无明显差异，最终22例患者中有4例（18％）接受了穿透性角膜移植术。最佳矫正视力等于或优于已知的6名无角膜移植患者的5名患者中的5名。结论：过敏和揉眼睛似乎是发生积液的重要危险因素。在某些未经手术的患者中，视觉结果是可以接受的。密切观察可以及早发现并治疗诸如穿孔和感染等并发症。

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