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LIQUID NITROGEN CRYOTHERAPY FOR SURFACE EYE DISEASE (AN AOS THESIS)

机译:液氮冷冻疗法用于表面性眼病(AOS论文)

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Purpose: To evaluate the effects of new treatments with liquid nitrogen cryotherapy on some external eye conditions. Methods: In this retrospective case study, 6 separate series from a single tertiary care referral center practice are described. Liquid nitrogen cryotherapy was used to treat conjunctival amyloidosis, primary pterygia, recurrent pterygia, advancing wavelike epitheliopathy (AWLE), superior limbic keratoconjunctivitis (SLK), and palpebral vernal keratoconjunctivitis (VKC). The main outcome measure was the resolution of the disease process after treatment. Results: Four patients with primary localized conjunctival amyloidosis were treated with liquid nitrogen cryotherapy. Two of them had recurrence of the amyloidosis, which cleared with subsequent treatment. Eighteen patients with primary pterygia had excision and cryotherapy with 1 recurrence. Of 6 subjects who presented with recurrent pterygia, 4 had a second recurrence after excision and cryotherapy. In 5 patients with AWLE, the condition resolved within 2 weeks without recurrence or the need for subsequent cryotherapy. Four patients with SLK were treated with liquid nitrogen cryotherapy. Disease recurred in 2 patients and 3 of 7 eyes, although subsequent cryotherapy eradicated SLK in all cases. Two patients and 3 eyelids with palpebral VKC were treated with liquid nitrogen cryotherapy. VKC recurred in all cases. Conclusions: Liquid nitrogen cryotherapy to the surface of the eye is effective in treating AWLE, and SLK. Excision followed by cryotherapy is successful in treating conjunctival amyloidosis and primary pterygia Liquid nitrogen cryotherapy is unsuccessful in the treatment of recurrent pterygia and VKC.
机译:目的:评估液氮冷冻疗法新疗法对某些外眼状况的影响。方法:在此回顾性案例研究中,描述了来自一个三级转诊中心实践的6个独立系列。液氮冷冻疗法用于治疗结膜淀粉样变,原发性翼状,肉,复发性翼状gia肉,行状波状上皮病(AWLE),上缘性角膜结膜炎(SLK)和睑缘春季角膜结膜炎(VKC)。主要结果指标是治疗后疾病进程的缓解。结果:4例原发性局部结膜淀粉样变性患者接受了液氮冷冻治疗。他们中的两个患有淀粉样变性病的复发,随后的治疗将其清除。 18例原发性翼状gia肉患者接受了切除和冷冻疗法,复发1例。在出现复发性翼状gia肉的6名受试者中,有4名在切除和冷冻治疗后再次复发。在5例AWLE患者中,病情在2周内缓解,没有复发,也不需要随后的冷冻治疗。 4名SLK患者接受了液氮冷冻治疗。该疾病在2例患者和7眼中的3眼中复发,尽管随后的冷冻治疗在所有情况下均消除了SLK。用液氮冷冻疗法治疗2例患者和3眼睑睑缘VKC。在所有情况下均会再次发生VKC。结论:液氮冷冻疗法可有效治疗AWLE和SLK。切除后冷冻治疗成功治疗结膜淀粉样变性和原发性翼状gia肉液氮冷冻治疗不能成功治疗复发性翼状and肉和VKC。

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