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首页> 外文期刊>Transactions of the American Ophthalmological Society. >Development of a quantitative method to measure vision in children with chronic cortical visual impairment.
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Development of a quantitative method to measure vision in children with chronic cortical visual impairment.

机译：开发一种定量方法以测量患有慢性皮质视力障碍的儿童的视力。

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PURPOSE: Cortical visual impairment (CVI) is the most common cause of bilateral vision impairment in children in Western countries. Better quantitative tools for measuring vision are needed to assess these children, to allow measurement of their visual deficit, and to monitor their response to treatment and rehabilitation. The author performed a series of experiments to assess the use of the sweep visual evoked potential (VEP) as a quantitative tool for measuring vision in CVI. METHODS: The first experiment was a reliability measure (test/retest) of VEP grating acuity thresholds of 23 children with CVI. To validate the VEP procedure, VEP grating acuity was compared to a clinical measure of vision, the Huo scale, and to a psychophysical measure of vision, the Teller Acuity Card procedure. Finally, the sweep VEP was tested as a tool for defining optimal luminance conditions for grating acuity in 13 children with CVI, by measuring grating thresholds under 2 different luminance conditions: 50 and 100 candela per square meter (cd/m2). RESULTS: Retest thresholds were similar to original thresholds (r2 = 0.662; P = .003, 1-tailed t test). Grating VEP measures correlate significantly with the clinical index (r2 = 0.63; P = .00004). Teller acuity measurements are also similar to VEP measures in children (r2 = 0.64; P = .0005) but show lower acuities compared to the VEP for children with particularly low vision. Finally, 3 of 13 children tested under 2 background luminance conditions showed paradoxical improvement in grating threshold with dimmer luminance. CONCLUSIONS: The sweep VEP tool is a reliable and valid means for measuring grating acuity in children with CVI. The tool also shows promise as a means of determining the optimal visual environment for children with CVI.
机译：目的：皮质视力障碍（CVI）是西方国家儿童双眼视力障碍的最常见原因。需要更好的量化视力的量化工具来评估这些儿童，评估其视力缺陷并监测他们对治疗和康复的反应。作者进行了一系列实验，以评估扫描视觉诱发电位（VEP）作为在CVI中测量视觉的定量工具的用途。方法：第一个实验是对23例CVI儿童的VEP光栅敏锐度阈值进行可靠性测量（测试/重新测试）。为了验证VEP程序，将VEP光栅敏锐度与视觉的临床测量值，Huo标度以及柜员视力卡程序与视觉的心理物理测量值进行了比较。最后，通过在2种不同的亮度条件下（每平方米50和100烛光（cd / m2））测量光栅阈值，测试了扫描VEP作为定义13个CVI儿童的光栅敏锐度最佳亮度条件的工具。结果：再测阈值与原始阈值相似（r2 = 0.662; P = 0.003，1尾t检验）。光栅VEP量度与临床指数显着相关（r2 = 0.63; P = .00004）。柜员视敏度测量值也类似于儿童的VEP测量值（r2 = 0.64; P = .0005），但与视力特别低下儿童的VEP相比，其视敏度较低。最终，在2个背景亮度条件下测试的13个孩子中的3个显示出光栅阈值随调光器亮度而反常的改善。结论：扫描VEP工具是一种可靠且有效的手段，用于测量CVI儿童的光栅敏锐度。该工具还显示了希望，可以为CVI儿童确定最佳的视觉环境。

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