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Guenther Gerisch and Dicityostelium, the microbial model for ameboid motility and multicellular morphogenesis [Review]

机译:Guenther Gerisch和Dicityostelium,类风疹运动和多细胞形态发生的微生物模型[综述]

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摘要

Beginning in 1960 and continuing to this day, Guenther Gerisch's work on the social ameba Dictyostelium discoideum has helped to make it the model organism of choice for studies of cellular activities that depend upon the actomyosin cytoskeleton. Gerisch has brought insight and quantitative rigor to cell biology by developing novel assays and by applying advanced genetic, biochemical and microscopic techniques to topics as varied as cell-cell adhesion, chemotaxis, motility, endocytosis and cytokinesis.
机译:从1960年开始一直延续到今天,Guenther Gerisch从事的社会阿米巴盘基网柄菌的研究已使其成为依赖于放线菌素细胞骨架的细胞活动研究的首选模型生物。 Gerisch通过开发新颖的测定方法以及将先进的遗传,生化和显微镜技术应用于诸如细胞-细胞粘附,趋化性,运动性,内吞作用和胞质分裂等主题,为细胞生物学带来了见解和严格的定量分析。

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