Medical molecular farming: production of antibodies, biopharmaceuticalsand edible vaccines in plants [Review]

Daniell H; Streatfield SJ; Wycoff K

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Medical molecular farming: production of antibodies, biopharmaceuticalsand edible vaccines in plants [Review]

机译：医学分子农业：在植物中生产抗体，生物制药和可食用疫苗[综述]

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The use of plants for medicinal purposes dates back thousands of years but genetic engineering of plants to produce desired biopharmaceuticals is much more recent. As the demand for biopharmaceuticals is expected to increase, it would be wise to ensure that they will be available in significantly larger amounts, on a cost-effective basis. Currently, the cost of biopharmaceuticals limits their availability. Plant-derived biopharmaceuticals are cheap to produce and store, easy to scale up for mass production, and safer than those derived from animals. Here, we discuss recent developments in this field and possible environmental concerns.

机译：将植物用于医学目的可以追溯到数千年前，但是对植物进行基因工程以生产所需的生物药物的历史要远得多。随着对生物药品的需求预计将增加，明智的做法是确保在具有成本效益的基础上大量使用它们。当前，生物药物的成本限制了它们的可用性。植物来源的生物药品生产和储存便宜，易于大规模生产，并且比动物来源的生物药品更安全。在这里，我们讨论了该领域的最新发展以及可能的环境问题。

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来源
《Trends in Plant Science》 |2001年第5期|共8页
作者
Daniell H; Streatfield SJ; Wycoff K;
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原文格式 PDF
正文语种 eng
中图分类植物学;
关键词
Transgenic tobacco plants; Mouth-disease virus; B surface-antigen; Monoclonal-antibody; Potato plants; Expression; Protein; Immunogenicity; Mice; Immunization;

机译：转基因烟草植物;口腔疾病病毒;B表面抗原;单克隆抗体;马铃薯植物;表达;蛋白质;免疫原性;小鼠;免疫;

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专利

1. Medical molecular farming: production of antibodies, biopharmaceuticalsand edible vaccines in plants [Review] [J] . Daniell H, Streatfield SJ, Wycoff K Trends in Plant Science . 2001,第5期

机译：医学分子农业：在植物中生产抗体，生物制药和可食用疫苗[综述]
2. Transgenic plants for the production of edible vaccines and antibodies for immunotherapy [J] . Mohanty Amitabh, Sharma Arun K., Singh Yogendra, Current science . 1999,第04期

机译：转基因植物，用于生产用于免疫疗法的可食用疫苗和抗体
3. Targeting and expression of antigenic proteins in transgenic plants for production of edible oral vaccines [Review] [J] . Korban SS In Vitro Cellular and Development Biology. Plant: Journal of the Tissue Culture Association . 2002,第3期

机译：在生产可食用口服疫苗的转基因植物中靶向和表达抗原蛋白[综述]
4. Chloroplast transgenic approach for the production of antibodies, biopharmaceuticals and edible vaccines [C] . H. Daniell, A. Dhingra, A. Fernandez-San Millan International Congress on Photosynthesis . 2001

机译：用于生产抗体，生物制药和食用疫苗的叶绿体转基因方法
5. Plant molecular farming for the production of industrial enzyme and vaccines. [D] . Nahampun, Hartinio. 2015

机译：植物分子农业，用于生产工业酶和疫苗。
6. Medical molecular farming: production of antibodies biopharmaceuticals and edible vaccines in plants [O] . Henry Daniell, Stephen J. Streatfield, Keith Wycoff -1

机译：医学分子农业：在植物中生产抗体生物制药和食用疫苗
7. Molecular farming: production of drugs and vaccines in higher plants [O] . Atsuhiko Shinmyo, Ko Kato 2010

机译：分子养殖：在高等植物中生产药物和疫苗

Medical molecular farming: production of antibodies, biopharmaceuticalsand edible vaccines in plants [Review]

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