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Tracking down the elusive early endosome

机译:追踪难以捉摸的早期内体

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Despite significant progress in understanding protein trafficking and compartmentation in plants, the identification and protein compartmentalization for organelles that belong to both the secretory and endocytic pathways have been difficult because protein trafficking has generally been studied separately in these two pathways. However, recent data indicate that the trans-Golgi network serves as an early endosome merging the secretory and endocytic pathways in plant cells. Here, we discuss the proteins identified as markers for post-Golgi compartments in these two pathways and propose that the trans-Golgi network is a pivotal organelle with multiple sorting domains for post-Golgi protein trafficking in plant cells.
机译:尽管在理解植物中蛋白质运输和分隔方面取得了重大进展,但是同时属于分泌和内吞途径的细胞器的鉴定和蛋白质分隔仍然很困难,因为通常在这两种途径中分别研究了蛋白质运输。然而,最近的数据表明,反式高尔基体网络作为融合植物细胞分泌和内吞途径的早期内体。在这里,我们讨论在这两个途径中被鉴定为高尔基体后区区隔标记的蛋白质,并提出反高尔基体网络是具有多个排序域的关键细胞器,用于植物细胞中高尔基体后蛋白质的运输。

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