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Programmed cell death in plants: lessons from bacteria?

机译:植物中的程序性细胞死亡:细菌的教训?

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Programmed cell death (PCD) has well-established roles in the development and physiology of animals, plants, and fungi. Although aspects of PCD control appear evolutionarily conserved between these organisms, the extent of conservation remains controversial. Recently, a putative bacterial PCD protein homolog in plants was found to play a significant role in cell death control, indicating a conservation of function between these highly divergent organisms. Interestingly, these bacterial proteins are thought to be evolutionarily linked to the Bcl-2 family of proteins. In this opinion article, we propose a new unifying model to describe the relationship between bacterial and plant PCD systems and propose that the underlying control of PCD is conserved across at least three Kingdoms of life.
机译:程序性细胞死亡(PCD)在动物,植物和真菌的发育和生理中具有公认的作用。尽管PCD控制的某些方面在这些生物之间似乎在进化上是保守的,但其保守程度仍存在争议。最近,发现植物中推测的细菌PCD蛋白同源物在细胞死亡控制中起着重要作用,表明这些高度分化的生物体之间功能的保守。有趣的是,这些细菌蛋白质被认为与蛋白质的Bcl-2家族进化相连。在这篇观点文章中,我们提出了一个新的统一模型来描述细菌和植物PCD系统之间的关系,并提出PCD的基本控制在至少三个生命王国中都得到了保留。

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